{"id":"W3134327766","doi":"10.1200/jco.2021.39.6_suppl.94","title":"Overall survival (OS) and metastasis-free survival (MFS) by depth of prostate-specific antigen (PSA) decline in the phase III PROSPER trial of men with nonmetastatic castration-resistant prostate cancer (nmCRPC) treated with enzalutamide (ENZA).","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Placebo; Hazard ratio; Prostate cancer; Urology; Post-hoc analysis; Internal medicine; Proportional hazards model; Prostate-specific antigen; Oncology; Gynecology; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006531102,0.0006327897,0.0008550916,0.0004943004,0.0002224075,0.0005468287,0.0004499652,0.000669427,0.001544389],"category_scores_gemma":[0.003047429,0.0002321412,0.002317384,0.0005852032,0.0004717926,0.0007141765,0.0007235142,0.002044624,0.0002101657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004390414,"about_ca_system_score_gemma":0.000538657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000788403,"about_ca_topic_score_gemma":0.002929384,"domain_scores_codex":[0.9984782,0.000999518,0.00007745129,0.0001681972,0.0001689765,0.0001075982],"domain_scores_gemma":[0.9978837,0.0008898786,0.0007398634,0.0001217716,0.0001059648,0.0002586448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4875217,0.002069279,0.3205077,0.004932679,0.01638035,0.0001674979,0.0003625778,0.004649831,0.004808138,0.001599811,0.009004286,0.1479961],"study_design_scores_gemma":[0.03116533,0.0645016,0.8737458,0.0008955974,0.01128171,0.0006142672,0.0001936322,0.003559637,0.002340119,0.002471899,0.009098003,0.000132383],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9548951,0.03648197,0.0007698695,0.0007010293,0.0001454603,0.0002957053,0.004720165,0.0000191471,0.001971596],"genre_scores_gemma":[0.9877933,0.00473759,0.001347663,0.0004130704,0.0001696585,0.0004405706,0.004188932,0.000009782042,0.000899579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006531102,"threshold_uncertainty_score":0.03454018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1175350813816396,"score_gpt":0.446998843956707,"score_spread":0.3294637625750674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}