{"id":"W3134363260","doi":"10.1002/jev2.12071","title":"Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses","year":2021,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"H2020 Marie Skłodowska-Curie Actions; H2020 Future and Emerging Technologies; H2020 European Research Council; Stichting voor de Technische Wetenschappen; Horizon 2020 Framework Programme","keywords":"Cell biology; Immune system; Microvesicles; Cell signaling; Biology; Population; Extracellular vesicle; Chemistry; Signal transduction; Immunology; Biochemistry; microRNA; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002184386,0.0003541545,0.0007498742,0.0004674543,0.0004047412,0.0002358446,0.0002532178,0.0002642166,0.0004094336],"category_scores_gemma":[0.0003353225,0.0003502947,0.0002654616,0.0003237829,0.0001658476,0.0007923666,0.00006650274,0.0008710505,0.0000122723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001523861,"about_ca_system_score_gemma":0.0001517423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005214688,"about_ca_topic_score_gemma":0.00006211501,"domain_scores_codex":[0.9961014,0.0009591884,0.001418272,0.0004274277,0.0005311421,0.0005625311],"domain_scores_gemma":[0.9979178,0.0003632052,0.0008266844,0.0002910378,0.0003518729,0.0002493858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001817755,0.000377988,0.004651049,0.0001519216,0.00005768123,0.0005390114,0.001662478,0.00005177965,0.9862528,0.0006572339,0.0001118881,0.00366834],"study_design_scores_gemma":[0.002744851,0.0005859885,0.03195223,0.0009129883,0.00009642119,0.0003164878,0.003106866,0.0004915693,0.9485255,0.007176908,0.003653062,0.000437056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9566538,0.03851475,0.002640733,0.001120225,0.0007360213,0.0002149993,0.00002833089,0.00004346955,0.00004769589],"genre_scores_gemma":[0.9930354,0.0004130468,0.005547593,0.0002212922,0.0004304591,0.000005649481,0.00002410426,0.00006569156,0.0002567406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0381017,"threshold_uncertainty_score":0.9998949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03299215244629632,"score_gpt":0.2827929911136692,"score_spread":0.2498008386673729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}