{"id":"W3134679540","doi":"10.1242/jcs.255307","title":"Development of conformational BRET biosensors that monitor ezrin, radixin and moesin activation in real time","year":2021,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Moesin; Ezrin; Radixin; Biology; Cell biology; Biochemistry; Cytoskeleton; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000687647,0.0006507902,0.0005477084,0.0004809026,0.0002007921,0.0003874819,0.0006024055,0.0009701003,0.000742516],"category_scores_gemma":[0.0008569501,0.0003488375,0.0003312041,0.0003063608,0.0004036227,0.0005699576,0.0004635652,0.001088307,0.0004334708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004247609,"about_ca_system_score_gemma":0.0001458399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002292834,"about_ca_topic_score_gemma":0.0004244298,"domain_scores_codex":[0.9994037,0.000134535,0.00003668174,0.0001510464,0.0001933024,0.00008059941],"domain_scores_gemma":[0.9995264,0.0001533456,0.0001429102,0.00005401401,0.00008317874,0.00004022676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002186073,0.00001452822,0.00008565543,0.00002120535,0.000003300304,0.00001477577,0.00001600962,0.00009770271,0.9985423,0.00007890429,0.0000213344,0.001082417],"study_design_scores_gemma":[0.000004737886,0.0000774664,0.0004859346,0.000002270034,0.000004992241,0.0001129735,0.00001721644,0.002905964,0.9958588,0.00005476828,0.0004657369,0.000009181294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7945649,0.001501261,0.2002365,0.0005103703,0.00009373249,0.0002157409,0.0004050022,0.0008859261,0.001586467],"genre_scores_gemma":[0.809117,0.001305462,0.184472,0.0002188822,0.00002370987,0.0004550195,0.0005704464,0.00008417841,0.00375329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009701003,"threshold_uncertainty_score":0.003636658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02380820793970967,"score_gpt":0.267914196654007,"score_spread":0.2441059887142973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}