{"id":"W3134851073","doi":"10.1016/s2213-8587(21)00019-x","title":"Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":178,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Novo Nordisk Fonden; Novo Nordisk","keywords":"Medicine; Liraglutide; Placebo; Type 2 diabetes; Diabetes mellitus; Internal medicine; Antibody; Endocrinology; Immunology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001444043,0.00206193,0.004489359,0.0004530346,0.0004373823,0.00122026,0.000994866,0.002611166,0.005509101],"category_scores_gemma":[0.001279626,0.0007350039,0.002403786,0.0004826482,0.001125924,0.001164308,0.0004204139,0.003751374,0.001034049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006262942,"about_ca_system_score_gemma":0.0007291527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001203032,"about_ca_topic_score_gemma":0.00227211,"domain_scores_codex":[0.9995829,0.0001763108,0.00003382459,0.00008790113,0.00003649662,0.00008251785],"domain_scores_gemma":[0.9994634,0.0001585721,0.0001052491,0.00004328825,0.00003655046,0.0001929897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9846146,0.001948984,0.0002772073,0.0007410517,0.001025318,0.00003789761,0.00002829028,0.0001221867,0.001804836,0.00005857255,0.0005663569,0.008774764],"study_design_scores_gemma":[0.9763264,0.02175072,0.0008172481,0.00002732862,0.0004098304,0.00002411409,0.00001140248,0.0001129904,0.0001441426,0.00005218736,0.0003137618,0.000009957691],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9691038,0.02103907,0.0008580646,0.001080908,0.001575215,0.002602709,0.001211866,0.000254078,0.00227431],"genre_scores_gemma":[0.9738563,0.01089763,0.001634698,0.002267024,0.001125451,0.003704481,0.001600736,0.0000465599,0.004867284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005509101,"threshold_uncertainty_score":0.01842982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01903826276283652,"score_gpt":0.2832448740454684,"score_spread":0.2642066112826318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}