{"id":"W3134867336","doi":"10.1002/ehf2.13262","title":"Fat-1 Transgenic Mice Rich in Endogenous Omega-3 Fatty Acids are Protected from Lipopolysaccharide-Induced Cardiac Dysfunction","year":2021,"lang":"en","type":"article","venue":"ESC Heart Failure","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Natural Science Foundation of China","keywords":"Lipopolysaccharide; Genetically modified mouse; Heart failure; Sepsis; Medicine; Transgene; Cardiac function curve; Endogeny; Polyunsaturated fatty acid; Immunohistochemistry; Blot; Internal medicine; Endocrinology; Immune system; Oxidative stress; Immunology; Biology; Fatty acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002661055,0.0003596736,0.0009057075,0.0002390966,0.0001619532,0.00005572923,0.00008119986,0.0004549845,0.0005824851],"category_scores_gemma":[0.0002164951,0.0003343682,0.0007720745,0.0008576372,0.00003644223,0.0001474355,0.00004069313,0.0009543423,0.0003115015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002722447,"about_ca_system_score_gemma":0.0003148548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00135446,"about_ca_topic_score_gemma":0.0009177101,"domain_scores_codex":[0.9972407,0.0003634817,0.0004690092,0.0007731041,0.0006398761,0.0005138524],"domain_scores_gemma":[0.9985307,0.00007592239,0.00007492231,0.0007549723,0.0002671104,0.0002963133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002197932,0.0002126872,0.1266085,0.00008389974,0.0005737649,0.0001686632,0.0007277483,0.00001787816,0.8675549,0.00000596085,0.001908797,0.001917411],"study_design_scores_gemma":[0.004585963,0.0001905602,0.3229031,0.000249108,0.0005426599,0.0002589005,0.002742762,0.00003457421,0.5583103,0.0000185888,0.1096063,0.0005572179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921731,0.001010902,0.0004136611,0.003056804,0.001827188,0.001013135,0.00007669527,0.000265143,0.0001633768],"genre_scores_gemma":[0.996658,0.0001031287,0.0009851904,0.0004274041,0.001049156,0.000124368,0.0002439692,0.00007035201,0.0003384289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3092446,"threshold_uncertainty_score":0.9999108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02232243144840126,"score_gpt":0.2354780669488997,"score_spread":0.2131556355004985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}