{"id":"W3134881293","doi":"10.1093/jcag/gwab002.229","title":"A231 THE MICROBIOTA-NOCICEPTORS-MICROGLIA AXIS CONTROLS THE DEVELOPMENT AND MAINTENANCE OF CHRONIC VISCERAL HYPERSENSITIVITY","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Nociceptor; TRPV1; Microglia; Dysbiosis; Visceral pain; Inflammation; Medicine; Immunology; Chronic pain; Microbiome; Priming (agriculture); Disease; Gut flora; Neuroscience; Nociception; Biology; Transient receptor potential channel; Bioinformatics; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002565743,0.0001577578,0.0004468866,0.00006984166,0.0003501387,0.00001938844,0.0004562195,0.0002294429,0.00009706589],"category_scores_gemma":[0.0006284235,0.00008764987,0.0002260821,0.0001411422,0.0003798415,0.00006416822,0.0001167374,0.001219205,0.000002723558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001184246,"about_ca_system_score_gemma":0.0007802066,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002690798,"about_ca_topic_score_gemma":0.07567451,"domain_scores_codex":[0.9964349,0.002169117,0.000607387,0.0001311928,0.0002029774,0.0004544873],"domain_scores_gemma":[0.9968693,0.0009700069,0.001267501,0.0001376046,0.0005888116,0.0001668115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001677514,0.0003245682,0.2436335,0.00007458464,0.003061979,0.00008936522,0.001309951,0.0007782847,0.6961036,0.0003268574,0.047204,0.005415788],"study_design_scores_gemma":[0.009322834,0.001198174,0.6969913,0.00009471113,0.0008926708,0.0009075843,0.0003874415,0.0005424438,0.07697514,0.0002796528,0.2121665,0.0002414865],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9524891,0.0003377161,0.00001039916,0.04525576,0.001442597,0.0002162166,0.00006122262,0.000002921639,0.0001840625],"genre_scores_gemma":[0.9918201,0.00005759273,0.00008670797,0.007390178,0.0001902318,0.000003299761,0.000002272425,0.000008285282,0.0004413533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6191285,"threshold_uncertainty_score":0.941192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02709297383943501,"score_gpt":0.3167183684028836,"score_spread":0.2896253945634486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}