{"id":"W3134881293","doi":"10.1093/jcag/gwab002.229","title":"A231 THE MICROBIOTA-NOCICEPTORS-MICROGLIA AXIS CONTROLS THE DEVELOPMENT AND MAINTENANCE OF CHRONIC VISCERAL HYPERSENSITIVITY","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Nociceptor; TRPV1; Microglia; Dysbiosis; Visceral pain; Inflammation; Medicine; Immunology; Chronic pain; Microbiome; Priming (agriculture); Disease; Gut flora; Neuroscience; Nociception; Biology; Transient receptor potential channel; Bioinformatics; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000150602,0.0004695589,0.0004352195,0.0005002614,0.0003590766,0.0008452434,0.0003051586,0.0005514338,0.002875612],"category_scores_gemma":[0.0002142813,0.0002604046,0.0005035928,0.0002069319,0.0003988011,0.0003394451,0.0004339056,0.001085868,0.0007582609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000445058,"about_ca_system_score_gemma":0.0004639277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008825626,"about_ca_topic_score_gemma":0.001042804,"domain_scores_codex":[0.999663,0.00003939071,0.00002087385,0.00009332662,0.00007318141,0.0001102723],"domain_scores_gemma":[0.9996717,0.00001405861,0.0001061481,0.00001788844,0.00004734957,0.0001428662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005016122,0.00004560306,0.001176836,0.0001047055,0.00002009998,0.0001457004,0.00003390775,0.0000817814,0.9941362,0.0002117095,0.000218926,0.003322719],"study_design_scores_gemma":[0.0002575242,0.002175638,0.240206,0.0002543295,0.0003127868,0.001783081,0.00104927,0.003968951,0.7271507,0.002203782,0.02054181,0.00009610221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822237,0.007448393,0.005109261,0.0003905553,0.0001909254,0.00005326402,0.0013402,0.0003061708,0.0029374],"genre_scores_gemma":[0.990196,0.002251428,0.001932801,0.0001959866,0.00004718748,0.0001298677,0.0006161588,0.00008119396,0.004549273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002875612,"threshold_uncertainty_score":0.009619951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02709297383943501,"score_gpt":0.3167183684028836,"score_spread":0.2896253945634486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}