{"id":"W3134904374","doi":"10.1186/s12879-021-06141-4","title":"Interferon-gamma release assay levels and risk of progression to active tuberculosis: a systematic review and dose-response meta-regression analysis","year":2021,"lang":"en","type":"review","venue":"BMC Infectious Diseases","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bill and Melinda Gates Foundation","keywords":"Medicine; Meta-analysis; Internal medicine; Tuberculosis; Interferon gamma release assay; Latent tuberculosis; Relative risk; Interferon gamma; Meta-regression; Random effects model; Immunology; Mycobacterium tuberculosis; Confidence interval; Pathology; Cytokine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02902912,0.003915661,0.02415008,0.007122966,0.0005480638,0.003652435,0.003434506,0.003282324,0.00283502],"category_scores_gemma":[0.06477722,0.002214004,0.06104947,0.007660377,0.000815582,0.002058522,0.00157142,0.002792135,0.0004088725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003537476,"about_ca_system_score_gemma":0.00347851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007196411,"about_ca_topic_score_gemma":0.008951697,"domain_scores_codex":[0.9729702,0.01841269,0.004377677,0.00194985,0.001810312,0.0004792187],"domain_scores_gemma":[0.9542767,0.03720395,0.005046496,0.001148984,0.002026377,0.0002974163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001860099,0.00002808048,0.004049832,0.1667845,0.8186229,0.0001585409,0.00005102716,0.001704085,0.0001553181,0.0001440646,0.0004451273,0.005996479],"study_design_scores_gemma":[0.0006439315,0.0001841236,0.002051812,0.01083923,0.9843968,0.00009472602,0.00002289922,0.0006750124,0.0001190511,0.000230933,0.0007187436,0.00002267038],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008444951,0.9865253,0.002635254,0.000390323,0.0002175087,0.0006958966,0.0006589952,0.00007821208,0.0003536791],"genre_scores_gemma":[0.2759574,0.7069402,0.009942489,0.001226022,0.0003383286,0.003661647,0.001157683,0.00008954474,0.0006866515],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02902912,"threshold_uncertainty_score":0.1535225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06469665963398566,"score_gpt":0.4134415712645735,"score_spread":0.3487449116305879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}