{"id":"W3134930933","doi":"10.1002/jsp2.1143","title":"Inorganic polyphosphates stimulates matrix production in human annulus fibrosus cells","year":2021,"lang":"en","type":"article","venue":"JOR Spine","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute on Aging; National Institutes of Health; Arthritis Society; Foundation for the National Institutes of Health","keywords":"Aggrecan; Extracellular matrix; Proteoglycan; Matrix metalloproteinase; Cell biology; Chemistry; Glycosaminoglycan; Anabolism; Intervertebral disc; Matrix (chemical analysis); Cell culture; Matrix Metalloproteinase 3; Biochemistry; Anatomy; Biology; Pathology; Medicine; Genetics; Osteoarthritis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001236582,0.0002586162,0.0001719991,0.0002058868,0.0001208336,0.0001839725,0.00006091967,0.0001803115,0.001586642],"category_scores_gemma":[0.0001353351,0.00007868961,0.0001885884,0.0001463807,0.0001220428,0.0001305175,0.0001353918,0.0002470324,0.0003422096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001270884,"about_ca_system_score_gemma":0.00008962573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004130343,"about_ca_topic_score_gemma":0.0006257736,"domain_scores_codex":[0.9998814,0.00002995535,0.00001293039,0.00002069477,0.000032518,0.00002255708],"domain_scores_gemma":[0.9999098,0.00004027628,0.00001273751,0.000008589376,0.00001119358,0.00001745238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003349106,0.00008681798,0.0003332123,0.0001142335,0.000004098139,0.0001615622,0.00005910459,0.00003346755,0.9967212,0.00002981782,0.00007823576,0.002043336],"study_design_scores_gemma":[0.0001066348,0.003377418,0.0194825,0.00002045917,0.00003293563,0.0008903827,0.0001304482,0.0008413583,0.969041,0.00007814976,0.005989837,0.000008924987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917774,0.003707694,0.0009917219,0.0001095469,0.00005380446,0.00007248334,0.0003889349,0.00003586612,0.002862558],"genre_scores_gemma":[0.9930593,0.001431313,0.001967385,0.00008125303,0.00004691702,0.00009090185,0.0006256017,0.000005558041,0.002691761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001586642,"threshold_uncertainty_score":0.005307853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01229314949463209,"score_gpt":0.2908929794371528,"score_spread":0.2785998299425207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}