{"id":"W3135033803","doi":"10.1186/s12902-021-00699-5","title":"Levothyroxine and the risk of adverse pregnancy outcomes in women with subclinical hypothyroidism: a systematic review and meta-analysis","year":2021,"lang":"en","type":"review","venue":"BMC Endocrine Disorders","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Jewish General Hospital; McGill University","funders":"","keywords":"Medicine; Levothyroxine; Observational study; Randomized controlled trial; Meta-analysis; Pregnancy; Cochrane Library; Subclinical infection; Adverse effect; Relative risk; Pediatrics; Obstetrics; MEDLINE; Systematic review; Confounding; Internal medicine; Confidence interval; Thyroid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.0006368798,0.0008351682,0.01639825,0.0003640112,0.00006216167,0.00001479678,0.0002098617,0.0001060949,0.00009305294],"category_scores_gemma":[0.001302914,0.0003704141,0.002531302,0.00121285,0.0003725383,0.00006848489,0.0001658337,0.0004311476,0.000003649228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005419338,"about_ca_system_score_gemma":0.0002016511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002661308,"about_ca_topic_score_gemma":0.0009455506,"domain_scores_codex":[0.9951097,0.001273224,0.001918309,0.0008179755,0.0004367207,0.0004440118],"domain_scores_gemma":[0.9954551,0.00174837,0.001279339,0.001258355,0.00008652062,0.0001723522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00009336792,0.0007257831,0.005790804,0.719675,0.2717299,0.00006807531,0.0001850792,0.000001772811,2.350064e-9,0.0001417286,0.00001549671,0.001572912],"study_design_scores_gemma":[0.005951298,0.0002396454,0.0008791078,0.03231692,0.9589064,0.00005699908,0.0004246121,0.000002835706,1.428834e-8,0.00004658619,0.0008161986,0.0003593916],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002146666,0.9928013,0.00002017175,0.0002617477,0.00001051836,0.006403249,0.0001660094,0.00002123743,0.000101109],"genre_scores_gemma":[0.001197944,0.9950131,0.000259006,0.0001355373,0.000002850644,0.002236166,0.00007731019,0.00006843167,0.001009687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6873581,"threshold_uncertainty_score":0.9998748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0426922464126802,"score_gpt":0.3406476490506296,"score_spread":0.2979554026379493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}