{"id":"W3135127507","doi":"10.1097/qad.0000000000002865","title":"Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis","year":2021,"lang":"en","type":"article","venue":"AIDS","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases","keywords":"Emtricitabine; Medicine; Pre-exposure prophylaxis; Renal function; Tenofovir; Placebo; Randomized controlled trial; Incidence (geometry); Internal medicine; Proteinuria; Kidney disease; Kidney; Urology; Human immunodeficiency virus (HIV); Antiretroviral therapy; Immunology; Pathology; Viral load; Men who have sex with men","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001251827,0.00034964,0.0007877587,0.0003239222,0.000530998,0.0006940521,0.0002627955,0.0006265684,0.0008209868],"category_scores_gemma":[0.003322491,0.000255443,0.0006168616,0.0004069783,0.0002716486,0.0003432908,0.00026194,0.0007779133,0.00006801517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004533944,"about_ca_system_score_gemma":0.000427256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002571407,"about_ca_topic_score_gemma":0.002396348,"domain_scores_codex":[0.9989312,0.0003994851,0.00009293071,0.0002095928,0.0002149566,0.0001518277],"domain_scores_gemma":[0.9987597,0.0002420381,0.0005871301,0.0001001806,0.0001315202,0.0001794343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.07168859,0.003659836,0.8821042,0.0004045839,0.001872265,0.0003472246,0.0007156489,0.0002367934,0.007610115,0.0001196067,0.0002662258,0.03097485],"study_design_scores_gemma":[0.000637957,0.01476199,0.9803193,0.00003425037,0.0006883275,0.0004062748,0.00009260397,0.0001847367,0.00233293,0.00009153347,0.0004359073,0.00001417938],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985138,0.0008239222,0.00008707405,0.00002781008,0.00001390279,0.00007510111,0.0001125841,0.000003993521,0.0003418702],"genre_scores_gemma":[0.9994606,0.0001472058,0.00006022045,0.00003661448,0.00001270144,0.00003028288,0.00007365828,5.758272e-7,0.0001780085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002571407,"threshold_uncertainty_score":0.006620407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127741664615726,"score_gpt":0.2971448575254248,"score_spread":0.2843706910638522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}