{"id":"W3135137467","doi":"10.1177/10600280211000351","title":"Transthyretin Amyloid Cardiomyopathy—Current and Future Therapies","year":2021,"lang":"en","type":"article","venue":"Annals of Pharmacotherapy","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pfizer (Canada)","funders":"","keywords":"Medicine; Transthyretin; Amyloidosis; Cardiomyopathy; Cardiac amyloidosis; Heart failure; Restrictive cardiomyopathy; Internal medicine; Intensive care medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00390815,0.0005216055,0.002591826,0.002642037,0.0002918786,0.002184514,0.000888703,0.00125016,0.006214721],"category_scores_gemma":[0.004582946,0.0003081391,0.00167859,0.002129894,0.0008087769,0.002843546,0.0008917723,0.001608495,0.001308492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001251079,"about_ca_system_score_gemma":0.002109149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007549857,"about_ca_topic_score_gemma":0.001802553,"domain_scores_codex":[0.9980592,0.0006814082,0.0006279399,0.000213365,0.000339126,0.00007888726],"domain_scores_gemma":[0.9954486,0.002372327,0.001415492,0.0001064261,0.0005013293,0.000155752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00111493,0.0001464622,0.002670991,0.1417489,0.001185516,0.0005977669,0.0002134067,0.0003948348,0.001205517,0.006049187,0.03044314,0.8142293],"study_design_scores_gemma":[0.0008720437,0.0008766669,0.009754907,0.3458917,0.004749009,0.005980656,0.0009041405,0.000757709,0.0009426856,0.01751731,0.6116097,0.0001434718],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004092549,0.9956345,0.0001329737,0.002613982,0.0001894606,0.00001940536,0.0001139708,0.000007958517,0.0008785432],"genre_scores_gemma":[0.008965091,0.9852785,0.001076713,0.002556474,0.001380122,0.00007096179,0.0002558873,0.000009349308,0.0004069226],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006214721,"threshold_uncertainty_score":0.02079028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02847950623786494,"score_gpt":0.3429902249473475,"score_spread":0.3145107187094826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}