{"id":"W3135159820","doi":"10.1002/mds.28551","title":"Type 2 Diabetes as a Determinant of Parkinson's Disease Risk and Progression","year":2021,"lang":"en","type":"review","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":236,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institutes of Health; Canada First Research Excellence Fund; Barts Charity; Consortium canadien en neurodégénérescence associée au vieillissement; National Institute for Health and Care Research; Fonds de Recherche du Québec - Santé; Michael J. Fox Foundation for Parkinson's Research","keywords":"Mendelian randomization; Observational study; Odds ratio; Meta-analysis; Medicine; Internal medicine; Confidence interval; Parkinson's disease; Type 2 diabetes; Diabetes mellitus; Disease; Dementia; Population; Oncology; Bioinformatics; Genetics; Biology; Genotype; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001259769,0.0004804549,0.001448821,0.0001705366,0.00008729678,0.00002506329,0.00009448652,0.0001416521,0.000161473],"category_scores_gemma":[0.0001214996,0.0003476077,0.0004566034,0.0002626737,0.00007857219,0.00004179164,0.0001509828,0.0001684379,0.00001760816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008308909,"about_ca_system_score_gemma":0.0003741246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002793666,"about_ca_topic_score_gemma":0.000007460967,"domain_scores_codex":[0.9980398,0.0001344754,0.0004390207,0.0006416955,0.0003973233,0.0003476819],"domain_scores_gemma":[0.9985696,0.00005919995,0.0004063642,0.0005175016,0.00005697795,0.0003903609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004143341,0.0007448705,0.01219372,0.01064244,0.0005626297,0.0001081311,0.00001791223,6.525055e-8,7.265384e-7,0.00004190601,0.0002522327,0.975394],"study_design_scores_gemma":[0.0009635752,0.0005144199,0.003366878,0.01811168,0.005416883,5.289158e-7,0.00003152885,0.00001641723,0.00001049845,0.0009293741,0.9703096,0.0003286278],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008247848,0.9896691,0.000004851735,0.00004186148,0.0001650991,0.001498048,0.0001673511,0.00003306216,0.0001728056],"genre_scores_gemma":[0.002045497,0.9964983,0.0001879942,0.0001620864,0.00003351002,0.0003330895,0.0004163542,0.00007044309,0.0002526796],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9750653,"threshold_uncertainty_score":0.9998976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01753954581789931,"score_gpt":0.3188665551870565,"score_spread":0.3013270093691572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}