{"id":"W3135178773","doi":"10.1016/j.isci.2021.102283","title":"Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesions","year":2021,"lang":"en","type":"article","venue":"iScience","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sixth Framework Programme; Deutsche Forschungsgemeinschaft; Foundation Fighting Blindness","keywords":"Haploinsufficiency; Interactome; Focal adhesion; Cell biology; Cell adhesion; Receptor; Cell migration; Biology; Proteomics; Chemistry; Cell; Phenotype; Genetics; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004073493,0.0001783894,0.0002436246,0.0001276187,0.0004136175,0.00009201406,0.0001128038,0.0001292308,0.000316421],"category_scores_gemma":[0.0005691517,0.0001553582,0.00006849133,0.000599023,0.0002003392,0.0001657896,0.0002945131,0.0002204724,0.0001324745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001769232,"about_ca_system_score_gemma":0.0002046058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006161362,"about_ca_topic_score_gemma":0.00005428163,"domain_scores_codex":[0.9977234,0.0001034561,0.0002724919,0.00068354,0.0007624548,0.0004546658],"domain_scores_gemma":[0.9987839,0.000143243,0.00008347448,0.0004009874,0.0002377027,0.0003506236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005879011,0.00007806539,0.0005837402,0.00006376907,0.000003179919,0.00005848925,0.0002035206,0.000001931356,0.9932176,0.00003836496,0.002766646,0.00292583],"study_design_scores_gemma":[0.0005374603,0.0002325143,0.001018802,0.0002234776,0.00001687532,0.00008276496,0.0002286339,0.01042882,0.9827625,0.00007035594,0.004228792,0.0001690614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941439,0.001455636,0.0005592084,0.002411164,0.00008879081,0.0005048039,0.000005237953,0.00006306106,0.0007682191],"genre_scores_gemma":[0.9782622,0.0002089448,0.005852931,0.0001815572,0.00005259465,0.00001704252,0.0000363603,0.00002566287,0.01536264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01588161,"threshold_uncertainty_score":0.6335323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702270446243214,"score_gpt":0.2729217487123998,"score_spread":0.2558990442499676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}