{"id":"W3135298146","doi":"10.1093/jcag/gwab002.012","title":"A13 A HIGH SALT DIET SYNERGIZES WITH UC MICROBIOTA TO INDUCE A PROINFLAMMATORY IMMUNE TONE IN IMMUNOCOMPETENT GNOTOBIOTIC MICE","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute; McMaster University","funders":"","keywords":"Proinflammatory cytokine; Feces; Immune system; Ulcerative colitis; Colitis; Specific-pathogen-free; Immunology; Inflammation; Flow cytometry; Biology; Inflammatory bowel disease; Pathogenesis; Gut flora; Microbiology; Internal medicine; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000350524,0.0007593995,0.000711252,0.001040111,0.0003111289,0.0005477345,0.0003402097,0.000703262,0.002388916],"category_scores_gemma":[0.0001852491,0.0003540561,0.0006037787,0.0003083874,0.0006108618,0.0003885279,0.0004173715,0.001567951,0.0005459114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002571363,"about_ca_system_score_gemma":0.0003167312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003732985,"about_ca_topic_score_gemma":0.0006985728,"domain_scores_codex":[0.999433,0.0001123255,0.00007878346,0.0001067668,0.0001198437,0.0001493203],"domain_scores_gemma":[0.9992415,0.00005483197,0.0001806943,0.00008481713,0.00004442614,0.0003937641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001525048,0.0004309112,0.0004544277,0.00003860737,0.00001006843,0.00008121177,0.00002236209,0.00002825667,0.9967096,0.00003189821,0.00004222471,0.0006253767],"study_design_scores_gemma":[0.0005530298,0.01844229,0.03511293,0.00005438308,0.0001070428,0.0009422947,0.0002593109,0.001286301,0.9405136,0.0001636597,0.002527921,0.00003725506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997343,0.0003934705,0.0007209441,0.0001367276,0.00005567914,0.00004970573,0.0004041396,0.00008915857,0.0008072836],"genre_scores_gemma":[0.9926726,0.000533731,0.002262412,0.0002658719,0.00005087938,0.0001645159,0.0007703434,0.00005144036,0.003228176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002388916,"threshold_uncertainty_score":0.007991731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00347399234209712,"score_gpt":0.20613877563658,"score_spread":0.2026647832944828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}