{"id":"W3135328033","doi":"10.1039/d1ra00038a","title":"<i>In silico</i> and <i>in vitro</i> design of cordycepin encapsulation in liposomes for colon cancer treatment","year":2021,"lang":"en","type":"article","venue":"RSC Advances","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Kasetsart University; Thailand Research Fund; Natural Sciences and Engineering Research Council of Canada; National Research Council of Thailand; Canada Research Chairs","keywords":"Cordycepin; In silico; Encapsulation (networking); Liposome; In vitro; Colorectal cancer; Chemistry; Medicine; Cancer; Biochemistry; Computer science; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009481596,0.00008563962,0.0001988512,0.00001425088,0.00002140601,0.000009591944,0.00004408591,0.0000456593,0.00002884114],"category_scores_gemma":[0.0000185169,0.00003891123,0.00002598331,0.0001933595,0.00001897482,0.0001343912,0.00001031587,0.00002873816,4.504733e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003568983,"about_ca_system_score_gemma":0.00001509381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008729879,"about_ca_topic_score_gemma":0.006804592,"domain_scores_codex":[0.9993386,0.00004877192,0.0001904092,0.0001976662,0.00005788257,0.0001666655],"domain_scores_gemma":[0.9994599,0.0004140921,0.00006208238,0.00002269277,0.00001591116,0.00002527963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002054427,0.00008943272,0.009557372,0.00001386769,0.000002456897,0.000006963543,0.00007441155,0.0007556278,0.9215545,0.00002791538,0.00001222216,0.06769978],"study_design_scores_gemma":[0.0009136429,0.000341122,0.03791077,0.0001008172,0.000009225211,0.000004023179,0.0002451376,0.002044716,0.9436482,0.001595215,0.01298038,0.0002067866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894158,0.009504739,0.000009506261,0.0005746828,0.00007003223,0.0002783939,0.0001038333,0.000004512931,0.00003853489],"genre_scores_gemma":[0.9910461,0.008123707,0.0003893208,0.0001298066,0.00004122738,0.00007264875,0.00002849971,6.470496e-7,0.0001680398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06749298,"threshold_uncertainty_score":0.3797122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02390690237859358,"score_gpt":0.2562922590453039,"score_spread":0.2323853566667103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}