{"id":"W3135473978","doi":"10.1007/s11912-021-01035-9","title":"Lack of Evidence Does Not Equal Lack of Benefit: Neoadjuvant Chemotherapy and Trimodality Therapy in Selected Patients with Muscle-Invasive Bladder Cancer","year":2021,"lang":"en","type":"letter","venue":"Current Oncology Reports","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Bladder cancer; Neoadjuvant therapy; Oncology; Chemotherapy; Cancer; Internal medicine; Cisplatin; Urology; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002635815,0.0005612671,0.001960784,0.0002175927,0.00003726213,0.0000104169,0.0001179396,0.0007182179,0.0003499932],"category_scores_gemma":[0.0001709384,0.0003415654,0.0001785793,0.0004288298,0.0003740019,0.00009847029,0.00006200604,0.001075642,5.01163e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004252362,"about_ca_system_score_gemma":0.002931621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007199339,"about_ca_topic_score_gemma":0.0004435604,"domain_scores_codex":[0.9963104,0.0002210814,0.001263285,0.001003705,0.0007195753,0.0004819751],"domain_scores_gemma":[0.9961504,0.0003690976,0.001507109,0.0006777309,0.00117887,0.0001168195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00187508,0.002170514,0.8721895,0.001514723,0.001288382,0.001562431,0.001675155,0.000003173519,0.001193952,0.000001506872,0.01709028,0.0994353],"study_design_scores_gemma":[0.01120753,0.00443025,0.9320261,0.004313272,0.0009440751,0.0001225332,0.00005373742,0.000002905553,0.01422176,0.0001118076,0.03200684,0.0005591265],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9567291,0.007546438,0.000007424856,0.03211931,0.001109382,0.002100285,0.0002897818,0.00002876868,0.00006957992],"genre_scores_gemma":[0.9386567,0.01826781,0.0001152786,0.04040977,0.001008184,0.0004241785,0.0006175383,0.0001282357,0.0003722517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09887617,"threshold_uncertainty_score":0.9999036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1637344394118777,"score_gpt":0.4056075239334881,"score_spread":0.2418730845216104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}