{"id":"W3135576201","doi":"10.1101/2021.03.11.434779","title":"The level of synovial human VEGFA, IL-8 and MIP-1α correlate with truncation of lubricin glycans in osteoarthritis","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Vetenskapsrådet; Göteborgs Universitet; AFA Försäkring","keywords":"Chemokine; Inflammation; Synovial fluid; Osteoarthritis; Immunology; Population; Proinflammatory cytokine; Chemistry; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001534257,0.0002902806,0.0002435104,0.0003923766,0.0001372202,0.0003068369,0.00005239213,0.0002735761,0.00197165],"category_scores_gemma":[0.0002579324,0.0001521403,0.0002190864,0.0001813659,0.0001623592,0.0001061058,0.0001661127,0.0003733766,0.000255829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008480951,"about_ca_system_score_gemma":0.00006092589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002592166,"about_ca_topic_score_gemma":0.0002352616,"domain_scores_codex":[0.9998369,0.00003180435,0.00002274821,0.00003333709,0.00004140856,0.00003375287],"domain_scores_gemma":[0.9998181,0.00003001981,0.00006975548,0.00001203363,0.00002457461,0.00004558724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001122263,0.00008375975,0.02150696,0.00007178474,0.00002277129,0.0002776959,0.00009328388,0.00004358119,0.9748325,0.00001728329,0.00004676716,0.001881439],"study_design_scores_gemma":[0.0000977751,0.004292926,0.6396649,0.0000428694,0.0001234551,0.004960585,0.0006089439,0.001180353,0.3469649,0.0001439523,0.0019005,0.00001874634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987618,0.0006031224,0.000246878,0.00001633827,0.000005683826,0.000009060754,0.0001676396,0.000008086346,0.0001813575],"genre_scores_gemma":[0.9988756,0.0001710218,0.0002535095,0.00001860202,0.000005884471,0.00001380268,0.0001939784,0.000001446972,0.0004661788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00197165,"threshold_uncertainty_score":0.00659585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0216898103452767,"score_gpt":0.2313874428754349,"score_spread":0.2096976325301582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}