{"id":"W3135662544","doi":"10.1016/s1470-2045(21)00019-x","title":"Pembrolizumab monotherapy in metastatic triple-negative breast cancer","year":2021,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Pembrolizumab; Triple-negative breast cancer; Metastatic breast cancer; Oncology; Breast cancer; Internal medicine; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003906539,0.0001791092,0.0005649396,0.0002029676,0.0001759275,0.0004416053,0.0001621317,0.0003398625,0.002282999],"category_scores_gemma":[0.0007506866,0.00009409007,0.0002343846,0.0002273059,0.0001071248,0.0003660064,0.0001299353,0.000864079,0.0005751566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005912976,"about_ca_system_score_gemma":0.0003700251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006704432,"about_ca_topic_score_gemma":0.002659364,"domain_scores_codex":[0.9999093,0.00003276942,0.000007333621,0.00001165894,0.00001678793,0.00002208243],"domain_scores_gemma":[0.999836,0.00006810242,0.00002827276,0.000007535825,0.00001983122,0.00004033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01216938,0.0003250938,0.00620146,0.001590583,0.0005268122,0.0005058871,0.0000788123,0.001215295,0.01619642,0.001110759,0.03955194,0.9205275],"study_design_scores_gemma":[0.02509222,0.03145561,0.2273232,0.004360069,0.004011638,0.01329841,0.0007325654,0.01061034,0.03063269,0.01083748,0.6414812,0.000164586],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.482822,0.4385957,0.0009080244,0.03298166,0.002456415,0.0001589993,0.001006832,0.0001948248,0.04087551],"genre_scores_gemma":[0.8935866,0.09214947,0.001057342,0.004081879,0.001037965,0.0001307628,0.0007133787,0.00002121972,0.007221338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002282999,"threshold_uncertainty_score":0.007637441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05430835432453917,"score_gpt":0.3755661800372451,"score_spread":0.3212578257127059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}