{"id":"W3135724721","doi":"10.1039/d0cs00495b","title":"Host–guest binding in water, salty water, and biofluids: general lessons for synthetic, bio-targeted molecular recognition","year":2021,"lang":"en","type":"review","venue":"Chemical Society Reviews","topic":"Supramolecular Chemistry and Complexes","field":"Chemistry","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Molecular recognition; Host (biology); Chemistry; Nanotechnology; Water chemistry; Environmental chemistry; Combinatorial chemistry; Molecule; Materials science; Organic chemistry; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003336746,0.0005855229,0.0007595236,0.0009979169,0.0003226517,0.0009344518,0.0004764762,0.0008363473,0.002567174],"category_scores_gemma":[0.0003779448,0.0003086407,0.0002685766,0.001018195,0.0006286968,0.00196842,0.0006987939,0.001564818,0.001559599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000515095,"about_ca_system_score_gemma":0.0005829041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005996681,"about_ca_topic_score_gemma":0.001216791,"domain_scores_codex":[0.9998704,0.00002107684,0.00001193157,0.00002942553,0.00004576421,0.00002133723],"domain_scores_gemma":[0.9999225,0.00004146146,0.000008614934,0.000003959872,0.00001421996,0.00000924519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000595669,0.00009621429,0.0001695987,0.02779401,0.00007125398,0.0004463144,0.0003891226,0.00112917,0.03356539,0.05891858,0.04455785,0.8328029],"study_design_scores_gemma":[0.000004333177,0.00006708742,0.0001801599,0.0009934288,0.00001780429,0.0004618613,0.00007986982,0.00009192433,0.002859876,0.004159432,0.9910712,0.00001305998],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004607197,0.9950907,0.0006332058,0.0004700531,0.0004022719,0.00000704292,0.00002263343,0.00001729294,0.002896137],"genre_scores_gemma":[0.002904657,0.9938356,0.0005479336,0.0003242816,0.0002276027,0.00001379326,0.00003360773,0.000004832924,0.002107676],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002567174,"threshold_uncertainty_score":0.008588076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07578492238891962,"score_gpt":0.3267469090429137,"score_spread":0.2509619866539941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}