{"id":"W3135737422","doi":"10.3390/curroncol28020106","title":"Comparative Efficacy and Safety of Immunotherapeutic Regimens with PD-1/PD-L1 Inhibitors for Previously Untreated Extensive-Stage Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis","year":2021,"lang":"en","type":"review","venue":"Current Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Atezolizumab; Etoposide; Pembrolizumab; Internal medicine; Oncology; Irinotecan; Durvalumab; Lung cancer; Adverse effect; Cancer; Chemotherapy; Immunotherapy; Colorectal cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0102594,0.001672824,0.01087119,0.003921978,0.0003515472,0.001813898,0.001341084,0.001299878,0.002233258],"category_scores_gemma":[0.01821374,0.0009498987,0.02931892,0.004334306,0.0004578455,0.00119883,0.0009262357,0.001395353,0.0002065272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001833088,"about_ca_system_score_gemma":0.001808688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004864919,"about_ca_topic_score_gemma":0.01078872,"domain_scores_codex":[0.9940362,0.003120198,0.001358154,0.0007394164,0.000594573,0.000151484],"domain_scores_gemma":[0.9893673,0.007894883,0.001633458,0.0003296186,0.0006283797,0.0001462876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003320388,0.00003812839,0.005747354,0.1723193,0.8013459,0.0000677354,0.00005130579,0.001209306,0.0003008089,0.0001508443,0.0005339307,0.01491497],"study_design_scores_gemma":[0.0006775645,0.0002173411,0.003668782,0.006719103,0.9869156,0.00004811819,0.00001797564,0.0003589474,0.00008964354,0.0002126399,0.001059213,0.00001511715],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01397751,0.9830502,0.001010199,0.0002653552,0.0001435922,0.0002494527,0.0008607931,0.00002566971,0.0004172772],"genre_scores_gemma":[0.4591045,0.5336005,0.002930508,0.001077193,0.000278769,0.0009146212,0.001674954,0.00003782238,0.0003810633],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01087119,"threshold_uncertainty_score":0.05425757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2618709932750546,"score_gpt":0.4974725700530229,"score_spread":0.2356015767779683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}