{"id":"W3135737422","doi":"10.3390/curroncol28020106","title":"Comparative Efficacy and Safety of Immunotherapeutic Regimens with PD-1/PD-L1 Inhibitors for Previously Untreated Extensive-Stage Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis","year":2021,"lang":"en","type":"review","venue":"Current Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Atezolizumab; Etoposide; Pembrolizumab; Internal medicine; Oncology; Irinotecan; Durvalumab; Lung cancer; Adverse effect; Cancer; Chemotherapy; Immunotherapy; Colorectal cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.001245423,0.0008413995,0.02120577,0.0002956997,0.0001579567,0.00002334153,0.0002036676,0.0002273733,0.00006906354],"category_scores_gemma":[0.000212241,0.0004935773,0.001546231,0.0013652,0.0004337102,0.00003473914,0.0002200216,0.0006326357,0.000001000614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007671266,"about_ca_system_score_gemma":0.001408751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000536027,"about_ca_topic_score_gemma":0.0001774476,"domain_scores_codex":[0.9944328,0.001750624,0.00183517,0.0009973001,0.0003504965,0.0006335912],"domain_scores_gemma":[0.9932219,0.002614167,0.002058015,0.0008253527,0.001056637,0.0002238909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0001873761,0.0002077662,0.00002439704,0.7844165,0.2098185,0.00002127359,0.0004645069,0.000008285864,2.221482e-7,0.00001760588,0.000927348,0.003906251],"study_design_scores_gemma":[0.001540841,0.0007538837,0.0000072104,0.1617832,0.6604095,0.00003445495,0.00007824921,0.00002675343,7.069811e-7,5.418601e-7,0.1750696,0.0002949837],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001549744,0.9806942,0.0001108005,0.0002274244,0.0001128298,0.01851019,0.0002380521,0.00002738602,0.00006357802],"genre_scores_gemma":[0.00003346974,0.99345,0.0002108419,0.0001077125,0.00009426267,0.005076203,0.0002941847,0.00006380015,0.0006695669],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6226332,"threshold_uncertainty_score":0.9997516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2618709932750546,"score_gpt":0.4974725700530229,"score_spread":0.2356015767779683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}