{"id":"W3135812366","doi":"10.1128/msystems.00233-21","title":"Identification and Development of Therapeutics for COVID-19","year":2021,"lang":"en","type":"article","venue":"mSystems","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"National Human Genome Research Institute; National Institutes of Health; Gordon and Betty Moore Foundation; National Heart, Lung, and Blood Institute; Fast Grants; National Institute of General Medical Sciences; American Heart Association","keywords":"Middle East respiratory syndrome; Identification (biology); Coronavirus; Middle East respiratory syndrome coronavirus; Adaptation (eye); Disease; Coronavirus disease 2019 (COVID-19); Pandemic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007742119,0.0005820938,0.0006982614,0.0009505439,0.0004038898,0.0014293,0.0005070562,0.001103329,0.004396574],"category_scores_gemma":[0.0005383439,0.0002485221,0.0007165973,0.0003597596,0.0006412868,0.001494776,0.0007944744,0.002503213,0.002113211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008246865,"about_ca_system_score_gemma":0.0007526051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003022037,"about_ca_topic_score_gemma":0.0007000903,"domain_scores_codex":[0.99976,0.00005498435,0.00002245082,0.00004505883,0.00006882102,0.00004875749],"domain_scores_gemma":[0.9998413,0.00004426629,0.00003215298,0.00001143902,0.00004405895,0.00002666282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005097208,0.0003876134,0.0006303301,0.008485664,0.0001786887,0.001194757,0.000420302,0.001877372,0.2477306,0.08597766,0.01935426,0.633253],"study_design_scores_gemma":[0.0001405536,0.002012402,0.001509537,0.001574241,0.0001637509,0.002490028,0.0002286596,0.001529801,0.09023441,0.01626724,0.8837696,0.00007977471],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02814822,0.8953529,0.02514675,0.00865187,0.002087615,0.0003116645,0.0006214891,0.0003269977,0.03935254],"genre_scores_gemma":[0.1329825,0.8287826,0.01547779,0.00424252,0.0008836216,0.0003297595,0.0006547405,0.0000627914,0.01658361],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004396574,"threshold_uncertainty_score":0.01470804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05121288281819442,"score_gpt":0.342347994864383,"score_spread":0.2911351120461886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}