{"id":"W3135830589","doi":"10.15252/embr.202052130","title":"Glial Hedgehog signalling and lipid metabolism regulate neural stem cell proliferation in Drosophila","year":2021,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; National Health and Medical Research Council; Australian Research Council; Peter MacCallum Foundation; University of Melbourne","keywords":"Cell biology; Drosophila (subgenus); Hedgehog; Hedgehog signaling pathway; Neural stem cell; Biology; Signalling; Metabolism; Lipid metabolism; Stem cell; Cell growth; Signal transduction; Genetics; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001018186,0.0003884733,0.0002151729,0.0005800265,0.0003537964,0.0007486248,0.0003424782,0.000341208,0.0008568236],"category_scores_gemma":[0.0001140012,0.0004423119,0.0002223723,0.0002311901,0.0004666554,0.0005313273,0.00055484,0.0005463507,0.0003395445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001137564,"about_ca_system_score_gemma":0.0003290457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003068811,"about_ca_topic_score_gemma":0.01003485,"domain_scores_codex":[0.9998796,0.00001365769,0.00001148411,0.00002315771,0.00004007342,0.00003213793],"domain_scores_gemma":[0.9998589,0.00001923338,0.00005209497,0.00001074816,0.00001852403,0.00004055849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001770937,0.000003800654,0.0006038595,0.00002627192,0.000005733919,0.0001152826,0.00003525718,0.00007305109,0.9968185,0.0006619383,0.00004913294,0.001430042],"study_design_scores_gemma":[0.00003475013,0.0000640285,0.03168683,0.00001240283,0.00003554999,0.000199709,0.0001893568,0.0009531725,0.9626569,0.0003299708,0.00382462,0.00001261099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900048,0.00287331,0.001651535,0.0001841613,0.00003129702,0.00001186527,0.0004169035,0.00006546952,0.00476077],"genre_scores_gemma":[0.9853938,0.001613866,0.002037003,0.0001223944,0.00001334001,0.00001887085,0.0004417976,0.00005939406,0.01029945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003068811,"threshold_uncertainty_score":0.008253694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007764674382607807,"score_gpt":0.2184450646829429,"score_spread":0.2106803903003351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}