{"id":"W3135908780","doi":"10.1093/jnci/djab029","title":"Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer","year":2021,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"KWF Kankerbestrijding; National Institute for Health and Care Research","keywords":"Endometrial cancer; Medicine; Hazard ratio; MLH1; Internal medicine; Lynch syndrome; Oncology; Confidence interval; MSH2; Cohort; Proportional hazards model; Gastroenterology; Cancer; Incidence (geometry); Urology; DNA mismatch repair; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007800761,0.0001418431,0.0002757033,0.0005927735,0.0001558165,0.0003169668,0.0002156032,0.0003260283,0.0009859435],"category_scores_gemma":[0.002766704,0.0001498957,0.0002127303,0.0004259321,0.0002509149,0.0002256942,0.000365274,0.0002311115,0.0001125268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001529131,"about_ca_system_score_gemma":0.0001924193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008680588,"about_ca_topic_score_gemma":0.001312583,"domain_scores_codex":[0.9995924,0.0001213576,0.00005231605,0.00008917764,0.00008369566,0.00006120544],"domain_scores_gemma":[0.9983233,0.0003521105,0.0008966363,0.0001009188,0.00009037247,0.0002366976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002009949,0.000006714125,0.9984523,0.000005919716,0.00001856534,0.00009918326,0.0000139381,0.00002577268,0.0001995576,0.000006565269,0.00002382917,0.0009466791],"study_design_scores_gemma":[0.000009377948,0.0001123582,0.9984219,0.00000508223,0.00002437171,0.001120924,0.00003603918,0.0001201172,0.00005734099,0.00001827129,0.00007195333,0.000002213087],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991317,0.0005776506,0.00002798135,0.00001837587,0.000001961044,0.000002603967,0.00009596155,0.000001332597,0.0001424414],"genre_scores_gemma":[0.9997517,0.0000957077,0.00002258306,0.000005006357,0.000003965933,0.000001986111,0.00009199748,4.707289e-7,0.0000265777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009859435,"threshold_uncertainty_score":0.004125476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04568203744579075,"score_gpt":0.3302565662266613,"score_spread":0.2845745287808706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}