{"id":"W3136076419","doi":"10.1016/j.annonc.2021.02.024","title":"Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium","year":2021,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"COVID-19 and healthcare impacts","field":"Medicine","cited_by":326,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"National Center for Advancing Translational Sciences; Merck Sharp and Dohme; EMD Serono; Bavarian Nordic; Sociedad Española de Oncología Médica; Swedish Orphan Biovitrum; Astellas Pharma; Janssen Pharmaceuticals; Korean Foundation for Cancer Research; Eisai; Natera; BeiGene; Daiichi-Sankyo; Aimmune Therapeutics; Daiichi Sankyo Europe; Agios Pharmaceuticals; Bayer Fund; Mirati Therapeutics; Incyte; Prostate Cancer Foundation; Hope Foundation; Halozyme; Clovis Oncology; American Society of Clinical Oncology; Heron Therapeutics; Sanofi; TG Therapeutics; Alexion Pharmaceuticals; Exelixis; Astellas Pharma US; Castle Biosciences; Dana-Farber Cancer Institute; PTC Therapeutics; Takeda Pharmaceuticals U.S.A.; Celgene; Ipsen Biopharmaceuticals; Genomic Health; F. Hoffmann-La Roche; National Comprehensive Cancer Network; American Cancer Society; American College of Radiology Imaging Network; Vanderbilt Institute for Clinical and Translational Research; Vanderbilt University; Harvard Medical School; Ipsen; Pancreatic Cancer Action Network; Bristol-Myers Squibb; Teva Pharmaceutical Industries; Foundation Medicine; GlaxoSmithKline; Dana-Farber/Harvard Cancer Center; Eli Lilly and Company; Genentech; AstraZeneca; National Cancer Institute; Genzyme; Kommission für Technologie und Innovation; Pfizer; Amgen; ECOG-ACRIN Cancer Research Group; Merck KGaA; National Institutes of Health; Conquer Cancer Foundation; Fonds de Recherche du Québec - Santé; Merck Canada; Array BioPharma","keywords":"Medicine; Internal medicine; Cancer; Absolute neutrophil count; Lung cancer; Chemotherapy; Neutropenia","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008184224,0.0001567535,0.0003087787,0.0005445666,0.0003493208,0.0005723523,0.0002407383,0.0002349012,0.0008103062],"category_scores_gemma":[0.003052884,0.0001083081,0.0003457481,0.001334955,0.0001765535,0.0002868694,0.0004881721,0.0003809963,0.0001093191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004098844,"about_ca_system_score_gemma":0.0006505842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008945731,"about_ca_topic_score_gemma":0.01058052,"domain_scores_codex":[0.9995483,0.0001019638,0.0000721194,0.00008462756,0.0001178862,0.00007518451],"domain_scores_gemma":[0.9962376,0.0007557077,0.001697945,0.0001668828,0.0006311986,0.0005106705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003045795,0.00000553375,0.9992868,0.00000450588,0.00001618414,0.00001760354,0.00001347737,0.00001387571,0.00001990075,0.000003199941,0.000127345,0.0004611386],"study_design_scores_gemma":[0.00000537144,0.00003286213,0.9993062,0.000006194447,0.00002059828,0.0001360397,0.00009468279,0.00008426508,0.00002683567,0.000004855858,0.0002798281,0.000002322289],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970523,0.0005617883,0.00008507467,0.0001600734,0.0000115017,0.00002033743,0.001528805,0.000003457631,0.0005766375],"genre_scores_gemma":[0.997956,0.0003070882,0.00006297511,0.00005434274,0.00002689848,0.00001392774,0.001509194,0.00000166836,0.00006789961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008945731,"threshold_uncertainty_score":0.01778734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2330244352279177,"score_gpt":0.516212991868426,"score_spread":0.2831885566405082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}