{"id":"W3136110687","doi":"10.1101/2021.03.17.435804","title":"Mitochondrial fission is required for proper nucleoid distribution within mitochondrial networks","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Université du Québec à Trois-Rivières; Université du Québec; Alberta Children's Hospital; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Children's Hospital Research Institute; Université du Québec à Trois-Rivières","keywords":"Nucleoid; Mitochondrial fission; Mitochondrial DNA; Biology; Mitochondrion; Cell biology; mitochondrial fusion; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002508438,0.0002512644,0.0003371181,0.0002225625,0.0004565918,0.0005454386,0.0002641381,0.0003156421,0.0007035355],"category_scores_gemma":[0.0007735574,0.0001984832,0.0002591217,0.0001798108,0.0003126271,0.0003628127,0.0005092087,0.0004583297,0.000222671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004816492,"about_ca_system_score_gemma":0.0003111031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000903455,"about_ca_topic_score_gemma":0.001009368,"domain_scores_codex":[0.9998453,0.00001847331,0.00001137645,0.00006001311,0.00005193325,0.00001296207],"domain_scores_gemma":[0.9995815,0.0001313399,0.0001267753,0.00004148714,0.00004982722,0.00006911145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001385922,0.00002642388,0.004810791,0.00007434269,0.00001782755,0.0001052076,0.00003939035,0.01846356,0.9698002,0.001428082,0.000162052,0.004933466],"study_design_scores_gemma":[0.00003308399,0.00009391536,0.0162096,0.00001159938,0.00002034878,0.0003942428,0.00005651678,0.3710279,0.6080773,0.001340342,0.002711266,0.00002379748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8546795,0.0003205167,0.1431345,0.00007935066,0.00002961627,0.00001881078,0.000289881,0.0006447876,0.0008029295],"genre_scores_gemma":[0.942171,0.0001584416,0.05664941,0.00001503337,0.000003686835,0.00002722404,0.0004473493,0.0001079341,0.0004199199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000903455,"threshold_uncertainty_score":0.00349462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01419663635220656,"score_gpt":0.2298135989583471,"score_spread":0.2156169626061405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}