{"id":"W3136240968","doi":"10.3389/fcimb.2021.621081","title":"Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Sinusitis and nasal conditions","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Provincial Health Services Authority; University of British Columbia","funders":"Canadian Institutes of Health Research; U.S. Food and Drug Administration; Killam Trusts; Michael Smith Health Research BC; University of California, San Francisco; Lotte and John Hecht Memorial Foundation","keywords":"Antimicrobial; Sinusitis; Medicine; Immunology; Anti-Infective Agents; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001029716,0.001614908,0.001052806,0.001442147,0.0005490847,0.0007860954,0.0009006226,0.0017212,0.004669848],"category_scores_gemma":[0.0002632014,0.0004996234,0.001241459,0.0004661406,0.000664803,0.0008072651,0.0006474041,0.003581199,0.001893064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005337366,"about_ca_system_score_gemma":0.0007354789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004143965,"about_ca_topic_score_gemma":0.0008112167,"domain_scores_codex":[0.9988539,0.0002093125,0.0001233973,0.0002169876,0.0003645559,0.0002317908],"domain_scores_gemma":[0.9994899,0.0000715194,0.0001483874,0.00008911409,0.00006259469,0.0001385628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001089423,0.001373199,0.0005759307,0.0003820936,0.00003488695,0.0003166695,0.0001053113,0.0005213243,0.9887216,0.001050889,0.0007943051,0.005034347],"study_design_scores_gemma":[0.0006125157,0.01707577,0.005189291,0.0002790977,0.0002413872,0.001936135,0.0002267954,0.005103173,0.9244326,0.001177687,0.04364375,0.00008192829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8674237,0.01686922,0.07789577,0.001880866,0.002300133,0.002938325,0.0141888,0.001836207,0.014667],"genre_scores_gemma":[0.8469623,0.01509026,0.08658019,0.001066786,0.0003758661,0.00606438,0.01186734,0.0003015494,0.03169129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004669848,"threshold_uncertainty_score":0.0156222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402556035142256,"score_gpt":0.2352515446079261,"score_spread":0.2212259842565035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}