{"id":"W3136318120","doi":"10.21203/rs.3.rs-297726/v1","title":"Intestinal Stem Cell Marker, ASCL2 Is a Novel Prognostic Predictor in Esophageal Adenocarcinoma","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Esophageal adenocarcinoma; Adenocarcinoma; Stem cell; Internal medicine; Cancer research; Stem cell marker; Oncology; Medicine; Biology; Cancer; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003452667,0.000379914,0.0004104064,0.0007080784,0.0002515928,0.0008572469,0.0003068767,0.0005439446,0.004400997],"category_scores_gemma":[0.001290409,0.0001761773,0.0002526958,0.0009446412,0.0002768006,0.000327534,0.0004913318,0.0006203833,0.00112494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001869844,"about_ca_system_score_gemma":0.0002062558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006994158,"about_ca_topic_score_gemma":0.0008952824,"domain_scores_codex":[0.9998657,0.00002301812,0.00001177453,0.00003064308,0.00003397338,0.00003487962],"domain_scores_gemma":[0.9995818,0.00009825062,0.000086151,0.00004743402,0.00006424871,0.0001221488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001783179,0.00007417382,0.9364548,0.0001268896,0.0001176778,0.0009856145,0.00009651439,0.0003636029,0.03053194,0.0001933694,0.003197072,0.02607502],"study_design_scores_gemma":[0.00005813691,0.0002461588,0.9785009,0.00003115203,0.0002250306,0.002613578,0.0003169378,0.002345942,0.008149632,0.0008240411,0.006672929,0.00001561252],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931006,0.001703129,0.0005611684,0.0003644964,0.00005595836,0.00001034872,0.00197561,0.00003926936,0.002189348],"genre_scores_gemma":[0.9929005,0.0006094896,0.0006442783,0.00007463791,0.0001013699,0.00001365569,0.003417722,0.00001720184,0.002221206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004400997,"threshold_uncertainty_score":0.01472282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1060972704753688,"score_gpt":0.3808361603150928,"score_spread":0.2747388898397239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}