{"id":"W3136339776","doi":"10.1097/ppo.0000000000000515","title":"Cytokine Release Syndrome Biology and Management","year":2021,"lang":"en","type":"review","venue":"The Cancer Journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Cytokine release syndrome; Chimeric antigen receptor; Immunosuppression; Immunotherapy; Immunology; Cytokine; Immune system; Medicine; Biology; Bioinformatics; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000434845,0.0006422128,0.001025153,0.00143907,0.0002257131,0.0008319684,0.0005928899,0.0008796281,0.001907582],"category_scores_gemma":[0.0006603446,0.0001679321,0.0004018724,0.0007949193,0.00038506,0.0007237759,0.0004347753,0.001770525,0.00107255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004725339,"about_ca_system_score_gemma":0.0008367826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006034523,"about_ca_topic_score_gemma":0.0007869859,"domain_scores_codex":[0.9998184,0.00003803019,0.00003099024,0.00002876676,0.00006346994,0.00002037824],"domain_scores_gemma":[0.9997757,0.00009590616,0.00004144063,0.000006367186,0.00005924372,0.00002132001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001016285,0.00006897968,0.0004551743,0.01074858,0.00008488676,0.00062751,0.00004199002,0.0003483,0.001571883,0.003556138,0.02396116,0.9584337],"study_design_scores_gemma":[0.00005560954,0.0002108373,0.00222693,0.007269888,0.0001937178,0.0137131,0.0001032502,0.0003452752,0.001754282,0.003325321,0.9707695,0.00003236825],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001815571,0.9983942,0.0001464912,0.00034785,0.0002073352,0.000004431341,0.000009626762,0.000006630835,0.0007019219],"genre_scores_gemma":[0.002738826,0.9955759,0.0002539084,0.0003408446,0.0004800817,0.00001067721,0.00003506514,0.000001596514,0.0005631538],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001907582,"threshold_uncertainty_score":0.006381512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0882306754738781,"score_gpt":0.4349938832934166,"score_spread":0.3467632078195386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}