{"id":"W3136384471","doi":"10.1371/journal.pbio.3000957","title":"An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans","year":2021,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Monash University","keywords":"Biology; Candida albicans; Virulence; Biofilm; Microbiology; Fungal protein; Mitochondrion; Genetics; Saccharomyces cerevisiae; Yeast; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000922914,0.0002599829,0.0001637258,0.0003160796,0.0002281677,0.0002364639,0.000169846,0.0002283052,0.0005398971],"category_scores_gemma":[0.00015749,0.00008113451,0.0001862352,0.0002205738,0.0001669819,0.00009703246,0.000205213,0.0002076573,0.0002114789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003165133,"about_ca_system_score_gemma":0.0001623587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008414961,"about_ca_topic_score_gemma":0.0008088254,"domain_scores_codex":[0.999944,0.000005963416,0.000005137204,0.00001368767,0.00001609731,0.00001519682],"domain_scores_gemma":[0.9999064,0.00001780674,0.00003022551,0.000005964404,0.00001011966,0.00002938584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001490886,0.0000223915,0.001617943,0.0000162441,0.000003951124,0.0002586619,0.00001437406,0.00007428122,0.9960595,0.0001034219,0.0000331905,0.001646934],"study_design_scores_gemma":[0.00007092569,0.0005577583,0.2265813,0.00002883916,0.00007611958,0.004091734,0.000214632,0.008980442,0.7533143,0.0003336413,0.005714174,0.00003614861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985958,0.0004370451,0.0004956443,0.00002548154,0.000005956824,0.000004006587,0.0001578304,0.00002189017,0.0002563628],"genre_scores_gemma":[0.9982361,0.0002038194,0.00079654,0.00001978469,0.000003532815,0.000003505513,0.0003376752,0.000008669916,0.0003904898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008414961,"threshold_uncertainty_score":0.002296507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01468714655540587,"score_gpt":0.268658943408177,"score_spread":0.2539717968527712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}