{"id":"W3136513189","doi":"10.1093/brain/awab132","title":"Deep grey matter injury in multiple sclerosis: a NAIMS consensus statement","year":2021,"lang":"en","type":"article","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; International Collaboration On Repair Discoveries; University of British Columbia; Douglas Mental Health University Institute; McGill University; University of Toronto; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; EMD Serono; National Institutes of Health; National Multiple Sclerosis Society; Genentech; Multiple Sclerosis Society; Race to Erase MS; Multiple Sclerosis Society of Canada; Patient-Centered Outcomes Research Institute; Sanofi Genzyme; Guerbet; Atara Biotherapeutics; Myelin Repair Foundation; Fondation Brain Canada; Natural Sciences and Engineering Research Council of Canada; Biogen; Celgene; Mitacs; Alexion Pharmaceuticals; Bristol-Myers Squibb; U.S. Department of Defense; Conrad N. Hilton Foundation; Sanofi; MedDay Pharmaceuticals; Teva Pharmaceutical Industries","keywords":"Grey matter; White matter; Multiple sclerosis; Magnetic resonance imaging; Neuroscience; Pathology; Medicine; Psychology; Psychiatry; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07539418,0.001544939,0.004062645,0.004606969,0.002620382,0.004955683,0.007504229,0.01582462,0.001759882],"category_scores_gemma":[0.0576397,0.0009582945,0.005060178,0.002888787,0.004845324,0.005809948,0.006993304,0.01705148,0.002197168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004355426,"about_ca_system_score_gemma":0.02475074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004377756,"about_ca_topic_score_gemma":0.00577823,"domain_scores_codex":[0.9707695,0.009216153,0.01045878,0.001752758,0.00663209,0.00117079],"domain_scores_gemma":[0.922692,0.03660672,0.006971562,0.002371918,0.02648365,0.004874074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005071609,0.0002847949,0.002947045,0.02565448,0.0005900095,0.0008180113,0.001268238,0.0009891925,0.002464703,0.01865177,0.431451,0.5143737],"study_design_scores_gemma":[0.0001239523,0.000215354,0.004157067,0.05862106,0.0007063084,0.001670876,0.0008447422,0.0003886918,0.0009504306,0.02079857,0.9114003,0.0001225463],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.001269206,0.4838029,0.005424842,0.468816,0.03487082,0.0004293488,0.0005842065,0.0001025855,0.004700108],"genre_scores_gemma":[0.02234448,0.616084,0.04823875,0.2540295,0.04769909,0.002114876,0.002694954,0.0001559826,0.006638371],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.07539418,"threshold_uncertainty_score":0.3987273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08241044504279577,"score_gpt":0.3284524191964794,"score_spread":0.2460419741536836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}