{"id":"W3136562864","doi":"10.1002/ardp.202000393","title":"Facile synthesis of C6‐substituted benz[4,5]imidazo[1,2‐<i>a</i>]quinoxaline derivatives and their anticancer evaluation","year":2021,"lang":"en","type":"article","venue":"Archiv der Pharmazie","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Quinoxaline; Chemistry; Combinatorial chemistry; Stereochemistry; Chemical synthesis; Bicyclic molecule; Medicinal chemistry; Organic chemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000162702,0.0003967925,0.0002518976,0.0002387105,0.0001620075,0.0001454119,0.0004166569,0.0002727877,0.002244767],"category_scores_gemma":[0.0001225239,0.0001292067,0.0002037267,0.0002572965,0.0001048595,0.0002009444,0.0002000713,0.0003101722,0.0008657253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000162281,"about_ca_system_score_gemma":0.0002405545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004057876,"about_ca_topic_score_gemma":0.0009449233,"domain_scores_codex":[0.9999012,0.00001431449,0.00000950936,0.00001523275,0.00003074267,0.00002898373],"domain_scores_gemma":[0.9999491,0.000005216607,0.00001261849,0.00000471873,0.00001669203,0.00001168093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008264235,0.0001273468,0.00009555364,0.0005008964,0.0000129826,0.0003078655,0.000058259,0.0006406532,0.9861196,0.0008968865,0.0005473559,0.01060998],"study_design_scores_gemma":[0.00006086406,0.00173288,0.001207208,0.00003649418,0.00002652825,0.0003104755,0.00003227777,0.001818161,0.9792504,0.0001948887,0.01529955,0.00003032688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8834445,0.01418589,0.06267548,0.0004347457,0.0003873327,0.001319523,0.003139506,0.0007397821,0.03367314],"genre_scores_gemma":[0.9729967,0.005315457,0.0163808,0.00007532586,0.00003315054,0.0002473706,0.000903747,0.00003291904,0.004014583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002244767,"threshold_uncertainty_score":0.00750953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05251035159133678,"score_gpt":0.3034469530242168,"score_spread":0.25093660143288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}