{"id":"W3136927683","doi":"","title":"Controlling Transgene Expression in the Central Nervous System For MRI-Guided Focused Ultrasound Delivery of Adeno-Associated Virus","year":2017,"lang":"","type":"dissertation","venue":"TSpace","topic":"Hermeneutics and Narrative Identity","field":"Arts and Humanities","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Adeno-associated virus; Transgene; Central nervous system; Neuroscience; Ultrasound; Medicine; Biology; Virology; Recombinant DNA; Radiology; Vector (molecular biology); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000245884,0.0003460627,0.0002333166,0.0002217132,0.0001310134,0.0003142824,0.0002588535,0.0002603231,0.001169443],"category_scores_gemma":[0.0001862371,0.0001532074,0.0002097963,0.0001203098,0.0002636656,0.0001780091,0.0001966173,0.0005050631,0.0004321224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003748008,"about_ca_system_score_gemma":0.0002792812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001068193,"about_ca_topic_score_gemma":0.001553294,"domain_scores_codex":[0.9997894,0.00002701516,0.00001639831,0.00005971426,0.00007286215,0.00003461462],"domain_scores_gemma":[0.9998821,0.00001956206,0.00003798303,0.00001248678,0.00003027177,0.00001758629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009266257,0.000005591112,0.00002478999,0.00001356978,7.514159e-7,0.00000843095,0.000006605864,0.0000191197,0.9993083,0.00004764958,0.00001329417,0.0005426252],"study_design_scores_gemma":[0.000005219318,0.0001756591,0.001032348,0.00001006568,0.000009780344,0.0001497081,0.00001361075,0.0008090418,0.9956317,0.00002361289,0.00213593,0.000003351356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9200915,0.002771045,0.07124753,0.0001417332,0.0001304939,0.0003106291,0.0005838222,0.0004357424,0.00428753],"genre_scores_gemma":[0.9237033,0.002837861,0.06253769,0.00009544044,0.00002383168,0.0003954357,0.001045023,0.0001061443,0.009255289],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001169443,"threshold_uncertainty_score":0.003912151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04712038438875207,"score_gpt":0.3092189339041051,"score_spread":0.2620985495153531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}