{"id":"W3137210471","doi":"10.1016/j.jtho.2021.01.263","title":"MA13.01 A Validation Study on DNA Repair Gene Variant for Lung Cancer Survival Prediction after Chemoradiation: A Secondary Analysis for RTOG-0617 Study","year":2021,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Medicine; Lung cancer; Oncology; ERCC2; DNA repair; Radiation therapy; Internal medicine; Chemoradiotherapy; Biomarker; Cohort; Gene; Genetics; Nucleotide excision repair; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00260551,0.001094156,0.001045031,0.0008435727,0.001019634,0.001628405,0.0009968893,0.001035185,0.006458357],"category_scores_gemma":[0.00384296,0.0003386593,0.002606064,0.001256502,0.0004979759,0.0005151488,0.0007889016,0.001393541,0.001716675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003324832,"about_ca_system_score_gemma":0.0008240505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0028989,"about_ca_topic_score_gemma":0.003378128,"domain_scores_codex":[0.9977034,0.0005868034,0.0002148366,0.0008958001,0.0002811387,0.0003180673],"domain_scores_gemma":[0.9967257,0.001234159,0.0005638531,0.0005551151,0.0004652409,0.0004559655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003924803,0.0001861136,0.9701886,0.00009756953,0.003020087,0.0005137095,0.0001492661,0.0003558019,0.01213762,0.0002320721,0.001905314,0.007289002],"study_design_scores_gemma":[0.0003466221,0.0008745334,0.9831042,0.00004685805,0.003548413,0.001164628,0.0001824246,0.001945507,0.003546775,0.0002915303,0.004920196,0.00002823512],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920337,0.0008929055,0.001466464,0.0002188819,0.0001171323,0.00004618949,0.003824593,0.00004271425,0.001357559],"genre_scores_gemma":[0.9937084,0.00009358967,0.0004946589,0.0001459357,0.00007584502,0.00004627223,0.003915655,0.00006069969,0.001458989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006458357,"threshold_uncertainty_score":0.02160531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02325730726251165,"score_gpt":0.3838620048712771,"score_spread":0.3606046976087655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}