{"id":"W3137253956","doi":"10.1038/s41419-021-03528-8","title":"Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Foundation; Medical Research Council; Versus Arthritis; Arthritis Research UK; University of Southampton; Research Councils UK; Université Laval","keywords":"Phagocytosis; Inflammation; Immune system; Immunology; Apoptosis; Efferocytosis; Pinocytosis; Biology; Neutrophil extracellular traps; Cell biology; Granulocyte; Macrophage; Receptor; Endocytosis; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004893491,0.000506969,0.0005363408,0.0003766952,0.0001781028,0.0007606072,0.0003214166,0.0005652274,0.001246877],"category_scores_gemma":[0.0005428665,0.0001437345,0.0003651191,0.0001830897,0.0004826321,0.000469388,0.0004354871,0.0007196585,0.0003172634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005122618,"about_ca_system_score_gemma":0.0003479902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002035187,"about_ca_topic_score_gemma":0.0002884686,"domain_scores_codex":[0.9992425,0.0001308659,0.0000882982,0.0001275974,0.0002528362,0.000157882],"domain_scores_gemma":[0.9994975,0.00005615731,0.0002176036,0.00009499498,0.00006954922,0.00006419773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005838323,0.00009568503,0.003134258,0.000280028,0.000033893,0.0006448317,0.00006182033,0.00009006609,0.9754269,0.001281632,0.0001376744,0.01822946],"study_design_scores_gemma":[0.00006445753,0.001300661,0.05220863,0.00005375694,0.00004385882,0.006019724,0.00009667091,0.001045261,0.9305676,0.0005498336,0.008034982,0.00001461616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9576859,0.02606303,0.01068625,0.0003167579,0.0001236531,0.0001184313,0.0002052893,0.0001850754,0.00461561],"genre_scores_gemma":[0.9936109,0.002108147,0.002242636,0.0001156658,0.00004406334,0.00003602005,0.0001279486,0.000009176711,0.001705406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001246877,"threshold_uncertainty_score":0.004171193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02754520209648963,"score_gpt":0.2347636072215676,"score_spread":0.207218405125078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}