{"id":"W3137425483","doi":"10.3389/fcell.2021.640712","title":"Dysregulated Gene Expression of Imprinted and X-Linked Genes: A Link to Poor Development of Bovine Haploid Androgenetic Embryos","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"CHIST-ERA; Natural Sciences and Engineering Research Council of Canada; Agencia Nacional de Investigación y Desarrollo; Agenția Națională pentru Cercetare și Dezvoltare","keywords":"Genomic imprinting; Biology; XIST; Blastocyst; Zygote; Genetics; Ploidy; Imprinting (psychology); Embryo; Embryogenesis; Gene; Uniparental disomy; Reprogramming; DNA methylation; Chromosome; X-inactivation; Gene expression; X chromosome; Karyotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001626761,0.0001659571,0.0002916725,0.0001185134,0.00004438899,0.000005428267,0.00008528768,0.0002157889,0.000009856927],"category_scores_gemma":[0.00003647064,0.0001596476,0.00002852452,0.0001441376,0.00008946507,0.000002702277,0.0002655291,0.00005231368,7.768135e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001826804,"about_ca_system_score_gemma":0.0001816232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006775577,"about_ca_topic_score_gemma":0.00002096738,"domain_scores_codex":[0.998783,0.00006774985,0.0004671188,0.0004116615,0.00006787065,0.0002025881],"domain_scores_gemma":[0.9995639,0.00001154957,0.0001080337,0.0001255353,0.00009265092,0.00009837584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001364771,0.00005322912,0.0564437,0.00005229774,0.00002705465,0.000002097119,0.0002418851,0.000007230751,0.9184476,0.000001241244,0.00003494805,0.02455223],"study_design_scores_gemma":[0.0008578678,0.000179155,0.02437033,0.00003019246,0.000007752049,0.000005254082,0.0002181877,0.00003807569,0.9708676,0.00006382994,0.003176545,0.000185224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757859,0.01029915,0.01340426,0.00003321775,0.0001471487,0.0001833211,0.00001883402,0.000003836445,0.0001243535],"genre_scores_gemma":[0.8034431,0.001178712,0.1949498,0.00003939247,0.00001758421,0.00001345979,0.000222834,0.00001215102,0.0001229555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1815456,"threshold_uncertainty_score":0.6510239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00795505099189943,"score_gpt":0.2243618026900182,"score_spread":0.2164067516981188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}