{"id":"W3137443677","doi":"10.3389/fcell.2021.641727","title":"Strength Through Unity: The Power of the Mega-Scaffold MACF1","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Cancer Research Society","keywords":"Cytoskeleton; Microtubule; Crosstalk; Cell biology; Biology; Cell polarity; Actin; Microfilament; Cell migration; Actin cytoskeleton; Scaffold protein; Cell; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003212684,0.0005644786,0.0006665152,0.0011826,0.0002258283,0.0008919592,0.0006307034,0.0008454653,0.003188881],"category_scores_gemma":[0.0004021703,0.0001734219,0.0002758111,0.0007691357,0.0003296722,0.001147993,0.0005772235,0.001488519,0.002171878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005491988,"about_ca_system_score_gemma":0.0007169641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006766914,"about_ca_topic_score_gemma":0.0009776144,"domain_scores_codex":[0.9999127,0.0000123855,0.0000105528,0.00001813503,0.00003303817,0.00001305759],"domain_scores_gemma":[0.9999127,0.00003792457,0.00001105091,0.000002857701,0.00002283251,0.00001245596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009344764,0.00002666266,0.0001121315,0.01029111,0.00005821524,0.0002582619,0.00006288939,0.0002141988,0.003565337,0.008244093,0.03369739,0.9433762],"study_design_scores_gemma":[0.000008126191,0.00003251881,0.0003230434,0.001002991,0.00003005259,0.0007474477,0.00002225476,0.00003088158,0.0006444176,0.0012283,0.9959226,0.000007467046],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002175066,0.9972399,0.0001566921,0.0004237305,0.0002585454,0.000003615831,0.0000258658,0.00001059733,0.001663543],"genre_scores_gemma":[0.001436796,0.9961668,0.0002221156,0.0003846249,0.0001577862,0.000007657059,0.00005843107,0.000003657163,0.001562172],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003188881,"threshold_uncertainty_score":0.01066786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02119278043952761,"score_gpt":0.2849575005397759,"score_spread":0.2637647201002483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}