{"id":"W3137465526","doi":"10.1111/febs.15829","title":"Molecular mechanisms regulating Proteinase‐Activated Receptors (PARs)","year":2021,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Effector; Biology; Signal transduction; G protein-coupled receptor; Mechanism (biology); Cell biology; Function (biology); Protease-activated receptor; Proteolytic enzymes; Enzyme; Biochemistry; Platelet; Immunology; Thrombin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002752146,0.0006903661,0.0007922326,0.001290808,0.0002511976,0.0009117033,0.0005146519,0.000864888,0.002358749],"category_scores_gemma":[0.000231574,0.0002207288,0.0003514441,0.0008598071,0.0003610391,0.000901714,0.0004800288,0.001230686,0.00232886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000426293,"about_ca_system_score_gemma":0.0005404024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003748521,"about_ca_topic_score_gemma":0.0004516894,"domain_scores_codex":[0.999887,0.00001481216,0.00001419206,0.00002158941,0.00004232616,0.00002004096],"domain_scores_gemma":[0.9999369,0.00001828904,0.0000157832,0.000002380317,0.00001779837,0.000008853605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001587959,0.0001147456,0.0002840908,0.01566126,0.0001113832,0.0007232002,0.0001253295,0.0005556426,0.03160431,0.01364849,0.02829696,0.9087159],"study_design_scores_gemma":[0.0000340535,0.0001734988,0.001458009,0.001523251,0.0001114199,0.00296297,0.00007539322,0.0001715816,0.007101661,0.003911134,0.9824479,0.00002909577],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005104805,0.9968305,0.0004072291,0.0003883652,0.0001900787,0.00001232607,0.00003910984,0.0000182807,0.001603619],"genre_scores_gemma":[0.002375313,0.9958585,0.0003384473,0.0001739788,0.0001971935,0.00001527071,0.00006166817,0.000001533119,0.0009780815],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002358749,"threshold_uncertainty_score":0.007890761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06160857085007201,"score_gpt":0.3385609795821611,"score_spread":0.2769524087320892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}