{"id":"W3137539669","doi":"10.1016/j.jaad.2021.03.032","title":"Tralokinumab does not impact vaccine-induced immune responses: Results from a 30-week, randomized, placebo-controlled trial in adults with moderate-to-severe atopic dermatitis","year":2021,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"LEO Pharma Research Foundation","keywords":"Medicine; Atopic dermatitis; Placebo; Randomized controlled trial; Dermatology; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001798791,0.001189841,0.003125597,0.0002663301,0.0004370835,0.001033078,0.0008130218,0.001491206,0.004005379],"category_scores_gemma":[0.001709034,0.0005428559,0.002570153,0.0002784602,0.0009831242,0.001071759,0.0002560198,0.002778942,0.0005999772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005997719,"about_ca_system_score_gemma":0.0006116955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00104346,"about_ca_topic_score_gemma":0.002432019,"domain_scores_codex":[0.9993025,0.0003006062,0.00006554779,0.0001543452,0.00005843494,0.0001184747],"domain_scores_gemma":[0.9990477,0.0003816622,0.0002253407,0.00006503629,0.00006043243,0.0002199011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9721586,0.003701158,0.0007945559,0.001384206,0.002264353,0.00005803772,0.00005361927,0.0002270979,0.003791379,0.00005202468,0.0004753133,0.01503965],"study_design_scores_gemma":[0.9235851,0.06670028,0.005913007,0.00008288157,0.002238463,0.00006495493,0.00004415888,0.0003091152,0.00050421,0.00008079894,0.0004551119,0.00002182124],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868486,0.0100002,0.0002746152,0.0004189812,0.0004413789,0.000616366,0.0004039032,0.00005623209,0.0009395722],"genre_scores_gemma":[0.9936991,0.003473205,0.0004101333,0.0005165318,0.0002772212,0.0004136852,0.000327027,0.00001356646,0.000869653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004005379,"threshold_uncertainty_score":0.0133993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01160480314334845,"score_gpt":0.294298535363703,"score_spread":0.2826937322203546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}