{"id":"W3137603116","doi":"10.1016/j.isci.2021.102337","title":"The converging roles of Batten disease proteins in neurodegeneration and cancer","year":2021,"lang":"en","type":"review","venue":"iScience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Trent University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Nova Scotia Health Research Foundation","keywords":"Neurodegeneration; Batten disease; Disease; Neuroscience; Cancer; Computational biology; Medicine; Biology; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495761,0.0001001466,0.0003567719,0.00004559185,0.00006750913,0.00002206,0.00009811098,0.00002962527,0.00001694029],"category_scores_gemma":[0.000075774,0.00005810147,0.00006987462,0.000237574,0.0001521339,0.00004403684,0.00003991305,0.00009688036,9.325099e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002507918,"about_ca_system_score_gemma":0.0006764981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001841228,"about_ca_topic_score_gemma":0.00002167277,"domain_scores_codex":[0.9992237,0.0000674957,0.0001981551,0.0002182172,0.0001792236,0.0001132245],"domain_scores_gemma":[0.999519,0.0000552107,0.000102809,0.0002149327,0.00003258355,0.00007548297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004517776,0.00002158026,0.0001824436,0.001501159,0.00001000313,0.00003130781,0.00005649744,0.000002489702,0.00002493256,0.0002713861,0.00002339346,0.9978703],"study_design_scores_gemma":[0.0003364896,0.0000427885,0.002533957,0.01869904,0.0003773762,0.00001393254,0.00005296111,0.00042267,0.0001518873,0.00005902511,0.9771102,0.0001996447],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002876964,0.9962634,0.00001180502,0.0002554169,0.00008520955,0.0004520778,0.00001319605,0.000005218583,0.00003667476],"genre_scores_gemma":[0.002334515,0.9971406,0.00001252607,0.00008409643,0.00005744915,0.0001272546,0.000006687252,0.000007874158,0.000229035],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9976707,"threshold_uncertainty_score":0.2369309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03454630868644935,"score_gpt":0.3524195952762164,"score_spread":0.317873286589767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}