{"id":"W3137635187","doi":"10.1002/smll.202006000","title":"Nanovaccine‐Based Strategies to Overcome Challenges in the Whole Vaccination Cascade for Tumor Immunotherapy","year":2021,"lang":"en","type":"review","venue":"Small","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Vaccination; Immunotherapy; Cascade; Computational biology; Medicine; Cancer research; Immunology; Biology; Immune system; Engineering; Chemical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001378513,0.0006135098,0.00163456,0.0004476404,0.0002180224,0.0001086902,0.0009658242,0.0005667469,0.0002554707],"category_scores_gemma":[0.0001615819,0.0004201869,0.0006867751,0.0004338574,0.00003532576,0.0001045373,0.00005894707,0.0006377169,0.0001738559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001401319,"about_ca_system_score_gemma":0.0007083101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000068741,"about_ca_topic_score_gemma":0.0001483534,"domain_scores_codex":[0.9963145,0.00158933,0.0008164021,0.000602865,0.00005713472,0.0006198264],"domain_scores_gemma":[0.9970391,0.001615459,0.0003252076,0.0008962366,0.0001110301,0.00001297241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002645801,0.0002514773,4.276989e-7,0.00240221,0.0003942836,0.00001508829,0.00120148,0.000003485882,0.001652808,0.001517578,0.0009011702,0.9913954],"study_design_scores_gemma":[0.001383878,0.0003991532,0.00008742576,0.002973657,0.0001308274,0.0001298065,0.001021401,4.456823e-7,0.0004875579,0.00006025179,0.992834,0.0004915543],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001713694,0.9953442,0.0002053652,0.0007380788,0.0008209089,0.002275986,0.0001166736,0.00005633946,0.000271141],"genre_scores_gemma":[0.0001813501,0.9957104,0.0001283747,0.0004931006,0.00007779092,0.001446847,0.0005329539,0.00009543509,0.001333766],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9919329,"threshold_uncertainty_score":0.999825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09954317980737848,"score_gpt":0.3461837869487223,"score_spread":0.2466406071413438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}