{"id":"W3137669495","doi":"10.3389/fimmu.2021.655697","title":"Hepatocellular Carcinoma Immune Landscape and the Potential of Immunotherapies","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":221,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche","keywords":"Oncolytic virus; Chimeric antigen receptor; Immune system; Immunotherapy; Hepatocellular carcinoma; Tumor microenvironment; Medicine; Cancer research; Immune checkpoint; Immunology; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005311511,0.000632939,0.000947012,0.001328363,0.0001979272,0.0008866016,0.0006695511,0.001153496,0.001964155],"category_scores_gemma":[0.0005691178,0.0001904108,0.000322051,0.000992718,0.0004816803,0.00116551,0.0006251375,0.001986768,0.001366123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007193852,"about_ca_system_score_gemma":0.0006832441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005005429,"about_ca_topic_score_gemma":0.0008397587,"domain_scores_codex":[0.9998527,0.00003243097,0.00001531403,0.00002172272,0.00005705589,0.00002079495],"domain_scores_gemma":[0.9997942,0.00009267956,0.00002147865,0.000006325977,0.00006015546,0.00002516455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001118067,0.0000698263,0.0001754111,0.009774026,0.00005513084,0.0002879834,0.00005717582,0.0004954208,0.003125963,0.008331427,0.04237427,0.9351416],"study_design_scores_gemma":[0.00001447615,0.0001051911,0.0005766572,0.001789299,0.00003897705,0.001276088,0.00004600448,0.0001187242,0.0005941149,0.002885993,0.9925407,0.00001380575],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009948602,0.9984114,0.00008694331,0.0003749346,0.0003735477,0.00000202297,0.000006352067,0.000004253313,0.0006409888],"genre_scores_gemma":[0.0009269922,0.9974607,0.0001084011,0.0003303713,0.0004486833,0.000005358734,0.00001985836,0.000001305628,0.0006983421],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001964155,"threshold_uncertainty_score":0.006570756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009621780757924834,"score_gpt":0.2229179002681705,"score_spread":0.2132961195102457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}