{"id":"W3137673666","doi":"10.3390/cancers13061299","title":"Lysosomal Calcium Channels in Autophagy and Cancer","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Lysosome; Intracellular; Cell biology; Extracellular; Organelle; Cancer cell; Biology; Calcium signaling; Chemistry; Cancer; Biochemistry; Apoptosis; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001253582,0.0003164435,0.0009360161,0.00008870548,0.0000375647,0.00003444196,0.0001579425,0.0003695088,0.0000657508],"category_scores_gemma":[0.000037468,0.0002962425,0.0002429876,0.0001892741,0.00007976039,0.000001891367,0.0001290238,0.0002268251,0.000003897477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046796,"about_ca_system_score_gemma":0.001242387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004609148,"about_ca_topic_score_gemma":0.00007405602,"domain_scores_codex":[0.9985791,0.000107707,0.0003079886,0.000591832,0.00009540505,0.0003179474],"domain_scores_gemma":[0.9994274,0.00001437364,0.000118233,0.0002903202,0.00003720236,0.0001124095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008419738,0.000008186928,0.000009852258,0.002590179,0.0001754275,0.00004352555,0.00004071872,0.0001094985,0.0004823614,0.00004742804,0.002871476,0.9936129],"study_design_scores_gemma":[0.0002181939,0.00002179051,0.000003733044,0.002247719,0.0001687816,0.000025151,0.00001136238,0.00001377431,0.0005587838,0.000002613986,0.9963977,0.0003303413],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001150214,0.9972721,0.00001625643,0.00001335853,0.00107833,0.0002114505,0.00008245801,0.000009301991,0.0001665428],"genre_scores_gemma":[0.0003449942,0.996898,0.00002906496,0.0001300905,0.001007139,0.0001709021,0.0001572295,0.00005719731,0.001205384],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9935263,"threshold_uncertainty_score":0.999949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04231059662276746,"score_gpt":0.3439213830897535,"score_spread":0.301610786466986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}