{"id":"W3137681283","doi":"10.1101/2021.03.23.436684","title":"Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; National Institutes of Health; Emory University; Fred Hutchinson Cancer Research Center; Sanofi Pasteur; Biological and Environmental Research; Fondation du CHUM; Argonne National Laboratory; U.S. Department of Energy; Sanofi; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; Children's Healthcare of Atlanta","keywords":"Virology; Antibody; Epitope; Neutralizing antibody; Neutralization; Coronavirus; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Biology; Coronavirus disease 2019 (COVID-19); Immunology; Medicine; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000292555,0.0004452664,0.0002913976,0.0007643405,0.0003406194,0.0003662233,0.0001848639,0.0003217275,0.002880341],"category_scores_gemma":[0.0004410004,0.0001570333,0.0002558827,0.000390492,0.0001685251,0.0001253815,0.000246985,0.0003826552,0.0007675648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001666216,"about_ca_system_score_gemma":0.0001442956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001773405,"about_ca_topic_score_gemma":0.0008928073,"domain_scores_codex":[0.9998066,0.00002924519,0.00002209833,0.00005955814,0.00003374339,0.00004887289],"domain_scores_gemma":[0.9997875,0.00003948573,0.0000268351,0.00002031547,0.00007014205,0.00005574321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001255585,0.0009588604,0.3620642,0.0001595545,0.00009801722,0.002341087,0.001146945,0.0001352051,0.5974464,0.0003690494,0.001845848,0.03217926],"study_design_scores_gemma":[0.0003293001,0.005430838,0.8852257,0.00005872393,0.000162503,0.01273402,0.0009997865,0.001107286,0.07496446,0.0003108582,0.01865411,0.00002252217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977405,0.0003596652,0.0004645671,0.00005229937,0.00002024056,0.00006622441,0.0003413373,0.00001160603,0.0009435652],"genre_scores_gemma":[0.9945278,0.0002306927,0.0009960729,0.0002442962,0.00007750931,0.00006457384,0.001982166,0.00001572977,0.001861098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002880341,"threshold_uncertainty_score":0.009635687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05106164703799541,"score_gpt":0.3345687167481949,"score_spread":0.2835070697101995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}