{"id":"W3137866446","doi":"10.1039/d1ob00199j","title":"Design, synthesis, and evaluation of positron emission tomography/fluorescence dual imaging probes for targeting facilitated glucose transporter 1 (GLUT1)","year":2021,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Medical Imaging Techniques and Applications","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Alberta Hospital Edmonton; University of Alberta","funders":"","keywords":"Chemistry; Glucose transporter; GLUT1; Positron emission tomography; In vivo; Glucose uptake; Glucose Transporter Type 1; Cancer cell; Imaging agent; Ex vivo; Fluorescence; Transporter; Cancer; Biochemistry; In vitro; Nuclear medicine; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005805577,0.0001458266,0.0002178333,0.00002655479,0.00006920607,0.0000147709,0.00006444047,0.00008522994,0.0001622612],"category_scores_gemma":[0.0004289658,0.0001363502,0.00008458858,0.0002330937,0.0001053741,0.00003500553,0.00002704205,0.0001053442,4.509123e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004003059,"about_ca_system_score_gemma":0.000219548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003907017,"about_ca_topic_score_gemma":6.028629e-8,"domain_scores_codex":[0.9987319,0.00004443604,0.0003041157,0.000369871,0.0003552701,0.0001944137],"domain_scores_gemma":[0.9990396,0.00005745888,0.00009195662,0.0002680459,0.0004078006,0.0001350841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002959366,0.0001320283,0.0003737169,0.0004241695,0.00003636028,0.00001432301,0.00007725062,8.036595e-8,0.9936743,0.000001681391,0.0003470898,0.004889376],"study_design_scores_gemma":[0.0005858532,0.0000184979,0.000206556,0.0003669414,0.0003926914,0.00007961311,0.000104874,0.004633892,0.9931937,0.0001183506,0.0001689552,0.0001300149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4934391,0.003141325,0.4999944,0.002412908,0.00001488473,0.0007855687,0.00003081788,0.0001166363,0.00006430926],"genre_scores_gemma":[0.9579746,0.00008556399,0.04153011,0.00005643062,0.00002502828,0.0001041524,0.0001766122,0.00002348282,0.00002400842],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.4645355,"threshold_uncertainty_score":0.55602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542433684266671,"score_gpt":0.281141672785287,"score_spread":0.2657173359426203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}