{"id":"W3138067909","doi":"10.1002/ped4.12252","title":"Pharmacokinetic variability of factor VIII concentrates in Chinese pediatric patients with moderate or severe hemophilia A","year":2021,"lang":"en","type":"article","venue":"Pediatric Investigation","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Beijing Municipal Administration of Hospitals; National Natural Science Foundation of China","keywords":"Medicine; Pharmacokinetics; Von Willebrand factor; In vivo; Internal medicine; Gastroenterology; Clearance; Clotting factor; Urology; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002052056,0.00022554,0.0004016879,0.0002124832,0.00005482319,0.00001825159,0.00007256227,0.0001187259,0.0003379673],"category_scores_gemma":[0.0005480858,0.0001474895,0.00005777112,0.001605968,0.00007586811,0.000175944,0.00004242387,0.0002564422,0.00001411482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001347682,"about_ca_system_score_gemma":0.0009835993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002664822,"about_ca_topic_score_gemma":0.00001054543,"domain_scores_codex":[0.9980401,0.0001917648,0.0004673684,0.0004092612,0.0005628574,0.0003286237],"domain_scores_gemma":[0.9985712,0.0002625857,0.0001490065,0.0002525061,0.0005223778,0.0002423481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005551582,0.000509289,0.9968761,0.0006376294,0.00002632244,0.00005212382,0.0004113497,0.00009531993,0.000440654,0.00001036922,0.00005708426,0.0003286161],"study_design_scores_gemma":[0.006207024,0.0003036218,0.9887196,0.00002484291,0.000190702,0.000006132675,0.00001652115,0.001664972,0.002335621,0.0003444644,0.000005843808,0.0001805895],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981977,0.0002508657,0.00001595534,0.0003595701,0.00009464331,0.0007731037,0.00005862561,0.00003469619,0.0002148903],"genre_scores_gemma":[0.9978919,0.0003550756,0.0007351497,0.00008272524,0.0003156028,0.0000384829,0.0002628182,0.00002422677,0.0002940022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008156419,"threshold_uncertainty_score":0.6014448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905077422599671,"score_gpt":0.2801875865934519,"score_spread":0.2611368123674552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}