{"id":"W3138113034","doi":"10.1097/pap.0000000000000298","title":"High-grade Transformation/Dedifferentiation in Salivary Gland Carcinomas: Occurrence Across Subtypes and Clinical Significance","year":2021,"lang":"en","type":"review","venue":"Advances in Anatomic Pathology","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Mucoepidermoid carcinoma; Pathology; Acinic cell carcinoma; Salivary gland; Myoepithelial cell; Carcinoma; Biology; Adenocarcinoma; Immunohistochemistry; Cancer research; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004467337,0.0003967901,0.002304107,0.0002214313,0.00004301856,0.00001758073,0.0001235601,0.0003829135,0.00002072279],"category_scores_gemma":[0.0001218497,0.0003130476,0.0002281085,0.0003695972,0.0002061683,0.0001783582,0.00004847955,0.0006082315,0.000009940109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001692017,"about_ca_system_score_gemma":0.000215804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000707874,"about_ca_topic_score_gemma":0.0006272437,"domain_scores_codex":[0.9970329,0.0004770947,0.00120342,0.0007374708,0.0001499148,0.0003991968],"domain_scores_gemma":[0.9985268,0.0006719916,0.0003266729,0.0003336434,0.00003425367,0.0001066819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00003630751,0.0005416918,0.3378409,0.00362308,0.00006337895,0.001790938,0.000239606,0.000001283752,8.079225e-8,0.0007069921,0.00002119756,0.6551345],"study_design_scores_gemma":[0.01463856,0.001116951,0.5604311,0.02941018,0.002081522,0.003255855,0.0005274797,0.00008170096,0.00001792441,0.00172903,0.3849733,0.001736338],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1032242,0.8949926,0.00003471143,0.00005922312,0.0005932548,0.0007590928,0.0002783266,0.00002276212,0.00003578081],"genre_scores_gemma":[0.1416634,0.8566663,0.0001993302,0.0000647899,0.0000892933,0.0001979367,0.00109456,0.00001865379,0.000005694775],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6533982,"threshold_uncertainty_score":0.9999322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04626948669858819,"score_gpt":0.4083246770840355,"score_spread":0.3620551903854473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}