{"id":"W3138272515","doi":"10.1016/j.bbamem.2021.183605","title":"Membrane binding properties of the C-terminal segment of retinol dehydrogenase 8","year":2021,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec; Fonds de recherche du Québec – Nature et technologies; Fondation CHU de Québec","keywords":"Palmitoylation; Rhodopsin; Membrane; Visual phototransduction; Chemistry; Tryptophan; Biophysics; Retinal; Biochemistry; C-terminus; Retinaldehyde; Peptide; Enzyme; Biology; Amino acid; Cysteine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001651987,0.000305594,0.00035278,0.00008691155,0.0001128922,0.00003108344,0.0004745849,0.0001670633,0.0000230204],"category_scores_gemma":[0.00008406922,0.0002199362,0.0003283052,0.000451382,0.0004148966,0.00001223633,0.0003618399,0.0001007939,0.000006993114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001048915,"about_ca_system_score_gemma":0.000301889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001988436,"about_ca_topic_score_gemma":0.000009213905,"domain_scores_codex":[0.9981762,0.0001539609,0.00050135,0.0004831714,0.0003616026,0.0003237589],"domain_scores_gemma":[0.9987631,0.00001682047,0.0003348698,0.0006267144,0.0001803156,0.0000781938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002105818,0.0002453019,0.00007228617,0.0003715874,0.0001661757,0.000004798605,0.0002159214,0.000003224722,0.9983223,0.00003487735,0.0002138822,0.0001390415],"study_design_scores_gemma":[0.0005520607,0.0001070101,0.0009556233,0.0001845954,0.00007280822,0.00003569358,0.0002768612,0.00001563806,0.9968238,0.0000121718,0.0006695904,0.000294154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976751,0.0004084661,0.000002601953,0.0008436071,0.000193073,0.0002719064,0.00006105397,0.00001512098,0.0005291361],"genre_scores_gemma":[0.9981339,0.0005679837,0.0001928601,0.0001594101,0.00007695649,0.00002149167,0.0001400746,0.00003537734,0.0006719697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498528,"threshold_uncertainty_score":0.8968738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01341515436635199,"score_gpt":0.2259961095386198,"score_spread":0.2125809551722678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}