{"id":"W3138272515","doi":"10.1016/j.bbamem.2021.183605","title":"Membrane binding properties of the C-terminal segment of retinol dehydrogenase 8","year":2021,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec; Fonds de recherche du Québec – Nature et technologies; Fondation CHU de Québec","keywords":"Palmitoylation; Rhodopsin; Membrane; Visual phototransduction; Chemistry; Tryptophan; Biophysics; Retinal; Biochemistry; C-terminus; Retinaldehyde; Peptide; Enzyme; Biology; Amino acid; Cysteine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001392077,0.000220591,0.0001594135,0.0001817724,0.0001897084,0.0002745604,0.0002940583,0.0002762682,0.002093144],"category_scores_gemma":[0.0004762275,0.0001293328,0.0001779994,0.0001486079,0.0001749322,0.0002299597,0.0001657289,0.0004949039,0.0008485593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004438914,"about_ca_system_score_gemma":0.0001515529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003181157,"about_ca_topic_score_gemma":0.001141559,"domain_scores_codex":[0.9998983,0.0000226553,0.000005010612,0.00002185379,0.00002456041,0.00002764592],"domain_scores_gemma":[0.9997863,0.00009040708,0.00002072815,0.00001624376,0.00004966146,0.00003656764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002661235,0.00001532023,0.000314961,0.00001351199,0.00000473834,0.00002876925,0.00003409692,0.00006223736,0.9985849,0.0001605641,0.00002864559,0.0004861269],"study_design_scores_gemma":[0.00001472591,0.00016416,0.00739219,0.000006907829,0.00001145459,0.0001593152,0.00009115505,0.002550321,0.9876556,0.0001240069,0.001817184,0.00001304871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972051,0.0005875762,0.0009404977,0.00005434262,0.00001016916,0.000004873139,0.0001069505,0.00001023363,0.001080267],"genre_scores_gemma":[0.995919,0.0002287571,0.0005456836,0.00003280048,0.000005204509,0.000005676098,0.0005059464,0.00001013085,0.002746718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003181157,"threshold_uncertainty_score":0.007002234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01341515436635199,"score_gpt":0.2259961095386198,"score_spread":0.2125809551722678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}