{"id":"W3138342733","doi":"10.1016/j.scitotenv.2021.146566","title":"Novel polar AhR-active chemicals detected in sediments of an industrial area using effect-directed analysis based on in vitro bioassays with full-scan high resolution mass spectrometric screening","year":2021,"lang":"en","type":"article","venue":"The Science of The Total Environment","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"National Research Foundation of Korea; Ministry of Oceans and Fisheries","keywords":"Bioassay; Aryl hydrocarbon receptor; Chemistry; Environmental chemistry; In vitro; Pharmacology; Biochemistry; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008241932,0.0003770747,0.0001212668,0.000400795,0.0001548993,0.0001627971,0.000125147,0.0002045506,0.0005357458],"category_scores_gemma":[0.00007460274,0.00009999608,0.0001480148,0.0001720271,0.0001708221,0.00009921506,0.0001396178,0.0001616786,0.0001470397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001083109,"about_ca_system_score_gemma":0.0001771884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001015003,"about_ca_topic_score_gemma":0.002050873,"domain_scores_codex":[0.9999382,0.000007343092,0.000003239265,0.00001833678,0.00002010936,0.00001267792],"domain_scores_gemma":[0.999962,0.000006356292,0.000009531274,0.000002426798,0.00001206984,0.000007658704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002314064,0.000005576283,0.0004322463,0.00001149884,0.000002785913,0.00002609038,0.000004078272,0.00002822062,0.9990189,0.000008619173,0.000004530141,0.0004343241],"study_design_scores_gemma":[0.000003779784,0.00016556,0.01195535,0.000001511961,0.00002273824,0.0001651982,0.00003726151,0.0003612861,0.9867827,0.00002332798,0.000477685,0.000003663849],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990649,0.0006830413,0.006995081,0.00003895854,0.00001447316,0.0000389553,0.0005656157,0.00006618178,0.0009486107],"genre_scores_gemma":[0.9891557,0.0007824905,0.007416821,0.00006501439,0.00000823061,0.00002937286,0.000578466,0.000007506824,0.00195639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015003,"threshold_uncertainty_score":0.002018213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01366470608687105,"score_gpt":0.2597438128395778,"score_spread":0.2460791067527067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}