{"id":"W3138429576","doi":"10.1021/acsptsci.1c00020","title":"Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer","year":2021,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"National Cancer Institute; Heffter Research Institute; Clinical and Translational Science Institute, New York University; National Institute on Drug Abuse; Riverstyx Foundation","keywords":"Distress; Suicidal ideation; Psilocybin; Clinical psychology; Psychiatry; Cancer; Depression (economics); Randomized controlled trial; Population; Psychology; Medicine; Intervention (counseling); Clinical trial; Psychotherapist; Internal medicine; Poison control; Suicide prevention; Hallucinogen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006413736,0.0001767752,0.0005507531,0.0001940149,0.0002467294,0.0001495767,0.0002088413,0.0002399004,0.0008729912],"category_scores_gemma":[0.002032775,0.0001280012,0.0003334781,0.000163862,0.0002142713,0.0001737544,0.0002381536,0.0006396329,0.00007831621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002458404,"about_ca_system_score_gemma":0.0003481628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009217523,"about_ca_topic_score_gemma":0.002508874,"domain_scores_codex":[0.9996856,0.0001746131,0.00002613081,0.0000277676,0.00004161979,0.00004436318],"domain_scores_gemma":[0.9995004,0.0001670814,0.0001668926,0.00003746646,0.00002631609,0.0001017648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.2967293,0.05610683,0.03707945,0.001574566,0.001313627,0.0002298161,0.001278177,0.0018793,0.06778424,0.0001830828,0.001374964,0.5344666],"study_design_scores_gemma":[0.02726177,0.4312032,0.527127,0.0001473572,0.0006758558,0.0002070975,0.0003785838,0.001963714,0.009554137,0.0002355866,0.001213185,0.00003250434],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992861,0.000247773,0.00008117671,0.00003896357,0.000009044405,0.00009689292,0.00003311298,0.00000940039,0.0001975773],"genre_scores_gemma":[0.9990768,0.0002142588,0.0003031116,0.00004647671,0.00001627399,0.0001402843,0.00004900677,0.000001563526,0.0001520449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009217523,"threshold_uncertainty_score":0.003391981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03157474105177098,"score_gpt":0.4015691196489571,"score_spread":0.3699943785971861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}