{"id":"W3138501536","doi":"10.1182/bloodadvances.2020002998","title":"Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles","year":2021,"lang":"en","type":"article","venue":"Blood Advances","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; Jewish General Hospital; McGill University and Génome Québec Innovation Centre; McGill University; McGill University Health Centre","funders":"McGill University Health Centre; McGill University","keywords":"Podoplanin; Microvesicles; Cancer research; Tissue factor; Biology; Cell biology; Glioma; Platelet activation; Chemistry; microRNA; Platelet; Immunology; Coagulation; Medicine; Internal medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009133441,0.00031081,0.0002216806,0.00003599145,0.000192824,0.00007565762,0.0002624779,0.0001207911,0.00004447906],"category_scores_gemma":[0.00009232705,0.0002824758,0.0001368033,0.0002439566,0.000154748,0.00002169739,0.000124117,0.0001376532,0.00004176218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000012777,"about_ca_system_score_gemma":0.0002605859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008633987,"about_ca_topic_score_gemma":0.0002122346,"domain_scores_codex":[0.9981083,0.0001052863,0.0003232218,0.0007226809,0.0003031505,0.0004373394],"domain_scores_gemma":[0.9987246,0.00001455558,0.0001835537,0.0006572656,0.0001584363,0.000261638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000318255,0.00146837,0.02925636,0.0001522676,0.00009154381,0.0009679362,0.0000480155,0.0002298933,0.9578471,0.0003650411,0.0001056397,0.009149561],"study_design_scores_gemma":[0.001347339,0.0008033406,0.002131975,0.00007731758,0.0002291924,0.0004382381,0.0002560775,0.0000388009,0.9533328,0.000426995,0.04039389,0.0005240344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644248,0.0328321,0.001007423,0.00007175425,0.00008843796,0.0004070331,0.00004257082,0.0000731473,0.001052718],"genre_scores_gemma":[0.9864916,0.000213735,0.00953227,0.00006237553,0.0002560211,0.0001073067,0.0005577822,0.00006848916,0.002710429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04028825,"threshold_uncertainty_score":0.9999627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009020714708177042,"score_gpt":0.2431352484620603,"score_spread":0.2341145337538832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}